Histoplasmosis as a cause for a positive Fungitell™ (I → 3)-β-D-glucan test

Lindsey Egan; Patricia Connolly; L. Joseph Wheat; Deanna Fuller; Thomas E. Davis; Kenneth S. Knox; Chadi A. Hage

doi:10.1080/13693780701642235

Histoplasmosis as a cause for a positive Fungitell™ (I → 3)-β-D-glucan test

Lindsey Egan, Patricia Connolly, L. Joseph Wheat, Deanna Fuller, Thomas E. Davis, Kenneth S. Knox, Chadi A. Hage

Research output: Contribution to journal › Article › peer-review

27 Scopus citations

Abstract

We evaluated the Fungitell™beta-glucan (BG) test with specimens from patients with presumed histoplasmosis. The sensitivity of the test was 87% in histoplasmosis cases and had a specificity of 68% with controls. Histoplasmosis should be considered as a possible cause for a positive BG test, but such results may be found with many other conditions that are clinically similar to this fungal disease. Therefore, there is a need to conduct confirmatory tests for histoplasmosis in the appropriate clinical setting.

Original language	English (US)
Pages (from-to)	93-95
Number of pages	3
Journal	Medical mycology
Volume	46
Issue number	1
DOIs	https://doi.org/10.1080/13693780701642235
State	Published - Feb 2008
Externally published	Yes

Keywords

Antigen detection
Beta-glucan
Histoplasmosis

ASJC Scopus subject areas

Infectious Diseases

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10.1080/13693780701642235

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title = "Histoplasmosis as a cause for a positive Fungitell{\texttrademark} (I → 3)-β-D-glucan test",

abstract = "We evaluated the Fungitell{\texttrademark}beta-glucan (BG) test with specimens from patients with presumed histoplasmosis. The sensitivity of the test was 87% in histoplasmosis cases and had a specificity of 68% with controls. Histoplasmosis should be considered as a possible cause for a positive BG test, but such results may be found with many other conditions that are clinically similar to this fungal disease. Therefore, there is a need to conduct confirmatory tests for histoplasmosis in the appropriate clinical setting.",

keywords = "Antigen detection, Beta-glucan, Histoplasmosis",

author = "Lindsey Egan and Patricia Connolly and Wheat, {L. Joseph} and Deanna Fuller and Davis, {Thomas E.} and Knox, {Kenneth S.} and Hage, {Chadi A.}",

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T1 - Histoplasmosis as a cause for a positive Fungitell™ (I → 3)-β-D-glucan test

AU - Egan, Lindsey

AU - Connolly, Patricia

AU - Wheat, L. Joseph

AU - Fuller, Deanna

AU - Davis, Thomas E.

AU - Knox, Kenneth S.

AU - Hage, Chadi A.

PY - 2008/2

Y1 - 2008/2

N2 - We evaluated the Fungitell™beta-glucan (BG) test with specimens from patients with presumed histoplasmosis. The sensitivity of the test was 87% in histoplasmosis cases and had a specificity of 68% with controls. Histoplasmosis should be considered as a possible cause for a positive BG test, but such results may be found with many other conditions that are clinically similar to this fungal disease. Therefore, there is a need to conduct confirmatory tests for histoplasmosis in the appropriate clinical setting.

AB - We evaluated the Fungitell™beta-glucan (BG) test with specimens from patients with presumed histoplasmosis. The sensitivity of the test was 87% in histoplasmosis cases and had a specificity of 68% with controls. Histoplasmosis should be considered as a possible cause for a positive BG test, but such results may be found with many other conditions that are clinically similar to this fungal disease. Therefore, there is a need to conduct confirmatory tests for histoplasmosis in the appropriate clinical setting.

KW - Antigen detection

KW - Beta-glucan

KW - Histoplasmosis

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ER -

Histoplasmosis as a cause for a positive Fungitell™ (I → 3)-β-D-glucan test

Abstract

Keywords

ASJC Scopus subject areas

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