Hippocampal contributions to cortical plasticity

L. Nadel, M. Moscovitch

Research output: Contribution to journalArticlepeer-review

107 Scopus citations


The hippocampal complex and neocortex are both integrally important in memory function, in particular as regards memory for episodes and knowledge about the world that is derived from them. It is traditionally assumed that the role of the hippocampus is time-limited, after which retrieval of episodic memory depends only upon neocortical stores. A number of lines of evidence indicate that this traditional view is incorrect. We propose that the hippocampal complex is always necessary for retrieval of episodes and their contextual frame, and that hippocampal-neocortical interactions contribute instead to the extraction of semantic information to be stored in the neocortex.

Original languageEnglish (US)
Pages (from-to)431-439
Number of pages9
Issue number4-5
StatePublished - Apr 5 1998
Externally publishedYes


  • Cognitive maps
  • Hippocampus
  • Memory consolidation
  • Neocortex

ASJC Scopus subject areas

  • Pharmacology
  • Cellular and Molecular Neuroscience


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