Highly stereoselective synthesis of aryl/heteroaryl-: C -nucleosides via the merger of photoredox and nickel catalysis

Yingying Ma, Shihui Liu, Yifan Xi, Hongrui Li, Kai Yang, Zhihao Cheng, Wei Wang, Yongqiang Zhang

Research output: Contribution to journalArticlepeer-review

24 Scopus citations

Abstract

A photoredox/nickel dual-catalyzed decarboxylative cross-coupling reaction of anomeric ribosyl/deoxyribosyl acids with aryl/heteroaryl bromides has been developed. The reaction proceeds smoothly under visible-light irradiation and features the using of cost-effective and easily handled catalysts and starting materials, which allows the highly stereoselective synthesis of diverse aryl/heteroaryl-C-nucleosides in moderate to high yields.

Original languageEnglish (US)
Pages (from-to)14657-14660
Number of pages4
JournalChemical Communications
Volume55
Issue number97
DOIs
StatePublished - 2019

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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