Abstract
The novel dual cooperative asymmetric aminocatalysis and Lewis acid catalysis has been successfully developed for promoting cascade Michael-cyclization reaction with high enantio-, regio- and chemo-selectivity. The simple and practical process affords a one-pot approach to synthetically useful cyclopentenes.
Original language | English (US) |
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Pages (from-to) | 1742-1744 |
Number of pages | 3 |
Journal | Tetrahedron Letters |
Volume | 51 |
Issue number | 13 |
DOIs | |
State | Published - Mar 31 2010 |
Externally published | Yes |
Keywords
- Cascade
- Michael
- Organocatalysis
- Pd catalysis
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry