High-resolution SPECT with a CdZnTe detector array and a scintillation camera

M. C. Wu, G. A. Kastis, S. J. Balzer, D. W. Wilson, H. B. Barber, H. H. Barrett, M. W. Dae, B. H. Hasegawa

Research output: Contribution to conferencePaperpeer-review

11 Scopus citations


The emerging significance of transgenic animal research has motivated the development of radionuclide imaging systems for mice and other small animals. In this work we compare the performance of a scintillation camera with a pinhole collimator (aperture diameter = 0.5 mm, magnification = 8-10) to that of a pixellated CdZnTe hybrid detector array with a parallel-hole collimator (pixel pitch = 0.380 mm, collimator aspect ratio = 27:1, collimator efficiency = 5×10-5) for SPECT. A "mouse heart" phantom (annular cavity filled with aqueous pertechnetate simulating myocardial perfusion, OD = 5.1 mm, ID = 1.6 mm) and a miniature Carlson grid phantom (3.2 mm cold squares, 4.8 mm pitch) were imaged. Both systems produced high quality images in which objects smaller than two millimeters were resolved. The pinhole system's cone-beam geometry offers advantages, such as an easily variable field of view, and disadvantages such as increased distortion and a decreased field of view close to the pinhole. The semiconductor detector and parallel-hole collimator provide excellent spatial resolution close to the collimator with a fixed field of view of 25 × 25 mm. We believe that both systems will find applications in small animal imaging.

Original languageEnglish (US)
StatePublished - 2000
Event2000 IEEE Nuclear Science Symposium Conference Record - Lyon, France
Duration: Oct 15 2000Oct 20 2000


Other2000 IEEE Nuclear Science Symposium Conference Record

ASJC Scopus subject areas

  • Radiation
  • Nuclear and High Energy Physics
  • Radiology Nuclear Medicine and imaging


Dive into the research topics of 'High-resolution SPECT with a CdZnTe detector array and a scintillation camera'. Together they form a unique fingerprint.

Cite this