High-resolution optical mapping of the right bundle branch in connexin-40 knockout mice reveals slow conduction

Houman Tamaddon; Dhananjay Vaidya; Alex Simon; David Paul; Jose Jalife; Gregory Morley

High-resolution optical mapping of the right bundle branch in connexin-40 knockout mice reveals slow conduction

Houman Tamaddon, Dhananjay Vaidya, Alex Simon, David Paul, Jose Jalife, Gregory Morley

Physiology

Research output: Contribution to journal › Conference article › peer-review

Abstract

A study was conducted to characterize the electrophysiological consequences of the null mutation of Cx40 gene (Cx40-/-) on impulse propagation in the specialized conduction system. High-resolution resolution video maps of voltage-dependent fluorescence from the ventricular epicardium and the right bundle (RBB) were obtained using a high-speed CCD camera while simultaneously recording volume conducted ECGs. The data represent the first direct demonstration of conduction defects in the specialized conduction system of Cx40-/-mice.

Original language	English (US)
Pages (from-to)	S-53
Journal	Annals of Biomedical Engineering
Volume	28
Issue number	SUPPL. 1
State	Published - 2000
Event	2000 Annual Fall Meeting of the Biomedical Engineering Society - Washington, WA, USA Duration: Oct 12 2000 → Oct 14 2000

ASJC Scopus subject areas

Biomedical Engineering

Cite this

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title = "High-resolution optical mapping of the right bundle branch in connexin-40 knockout mice reveals slow conduction",

abstract = "A study was conducted to characterize the electrophysiological consequences of the null mutation of Cx40 gene (Cx40-/-) on impulse propagation in the specialized conduction system. High-resolution resolution video maps of voltage-dependent fluorescence from the ventricular epicardium and the right bundle (RBB) were obtained using a high-speed CCD camera while simultaneously recording volume conducted ECGs. The data represent the first direct demonstration of conduction defects in the specialized conduction system of Cx40-/-mice.",

author = "Houman Tamaddon and Dhananjay Vaidya and Alex Simon and David Paul and Jose Jalife and Gregory Morley",

year = "2000",

language = "English (US)",

volume = "28",

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journal = "Annals of Biomedical Engineering",

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number = "SUPPL. 1",

note = "2000 Annual Fall Meeting of the Biomedical Engineering Society ; Conference date: 12-10-2000 Through 14-10-2000",

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T1 - High-resolution optical mapping of the right bundle branch in connexin-40 knockout mice reveals slow conduction

AU - Tamaddon, Houman

AU - Vaidya, Dhananjay

AU - Simon, Alex

AU - Paul, David

AU - Jalife, Jose

AU - Morley, Gregory

PY - 2000

Y1 - 2000

N2 - A study was conducted to characterize the electrophysiological consequences of the null mutation of Cx40 gene (Cx40-/-) on impulse propagation in the specialized conduction system. High-resolution resolution video maps of voltage-dependent fluorescence from the ventricular epicardium and the right bundle (RBB) were obtained using a high-speed CCD camera while simultaneously recording volume conducted ECGs. The data represent the first direct demonstration of conduction defects in the specialized conduction system of Cx40-/-mice.

AB - A study was conducted to characterize the electrophysiological consequences of the null mutation of Cx40 gene (Cx40-/-) on impulse propagation in the specialized conduction system. High-resolution resolution video maps of voltage-dependent fluorescence from the ventricular epicardium and the right bundle (RBB) were obtained using a high-speed CCD camera while simultaneously recording volume conducted ECGs. The data represent the first direct demonstration of conduction defects in the specialized conduction system of Cx40-/-mice.

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M3 - Conference article

AN - SCOPUS:0034498465

SN - 0090-6964

VL - 28

SP - S-53

JO - Annals of Biomedical Engineering

JF - Annals of Biomedical Engineering

IS - SUPPL. 1

T2 - 2000 Annual Fall Meeting of the Biomedical Engineering Society

Y2 - 12 October 2000 through 14 October 2000

ER -

High-resolution optical mapping of the right bundle branch in connexin-40 knockout mice reveals slow conduction

Abstract

ASJC Scopus subject areas

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