TY - GEN
T1 - High Resolution Imaging of Superior Sagittal Lymphatic Vasculature in Dedicated Brain SPECT
AU - Kalluri, Kesava S.
AU - Mathur, Parth
AU - Pells, Sophia
AU - Auer, Benjamin
AU - May, Micaehla
AU - Segars, Paul
AU - Kuo, Phillip H.
AU - Furenlid, Lars R.
AU - King, Michal A.
N1 - Publisher Copyright:
© 2022 IEEE.
PY - 2022
Y1 - 2022
N2 - Better understanding of the function and role of the cerebral lymphatic and glymphatic vasculature is required to understand their role in circulation, waste removal, diagnosing age related impairments, and design of novel therapeutic agents. AdaptiSPECT-C, a dedicated brain SPECT imaging system is being developed for clinical and dynamic imaging, and to aide in the development of novel imaging agents and therapeutics. AdaptiSPECT-C is designed as a modular multipinhole SPECT camera, capable of achieving high resolution and high sensitivity, with patient head motion tracking and correction. Herein, through simulated imaging we report our results towards high spatial resolution imaging (0.5 mm) of the superior sagittal lymphatic vasculature modeled in the XCAT phantom.
AB - Better understanding of the function and role of the cerebral lymphatic and glymphatic vasculature is required to understand their role in circulation, waste removal, diagnosing age related impairments, and design of novel therapeutic agents. AdaptiSPECT-C, a dedicated brain SPECT imaging system is being developed for clinical and dynamic imaging, and to aide in the development of novel imaging agents and therapeutics. AdaptiSPECT-C is designed as a modular multipinhole SPECT camera, capable of achieving high resolution and high sensitivity, with patient head motion tracking and correction. Herein, through simulated imaging we report our results towards high spatial resolution imaging (0.5 mm) of the superior sagittal lymphatic vasculature modeled in the XCAT phantom.
KW - Brain SPECT
KW - Lymphatic Vasculature
KW - MPH
UR - http://www.scopus.com/inward/record.url?scp=85185370730&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85185370730&partnerID=8YFLogxK
U2 - 10.1109/NSS/MIC44845.2022.10398996
DO - 10.1109/NSS/MIC44845.2022.10398996
M3 - Conference contribution
AN - SCOPUS:85185370730
T3 - 2022 IEEE NSS/MIC RTSD - IEEE Nuclear Science Symposium, Medical Imaging Conference and Room Temperature Semiconductor Detector Conference
BT - 2022 IEEE NSS/MIC RTSD - IEEE Nuclear Science Symposium, Medical Imaging Conference and Room Temperature Semiconductor Detector Conference
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 2022 IEEE Nuclear Science Symposium, Medical Imaging Conference, and Room Temperature Semiconductor Detector Conference, IEEE NSS MIC RTSD 2022
Y2 - 5 November 2022 through 12 November 2022
ER -