High-resolution imager for digital mammography: Physical characterization of a prototype sensor

Sankararaman Suryanarayanan, Andrew Karellas, Srinivasan Vedantham, Steven K. Onishi

Research output: Contribution to journalArticlepeer-review

18 Scopus citations


The physical performance characteristics of a high-resolution sensor module for digital mammography were investigated. The signal response of the imager was measured at various detector entrance air kerma and was found to be linear. The spatial resolution was determined by measuring the presampling modulation transfer function, MTF(f), of the system. The noise power spectra, NPS(f), of the system were estimated using 26 kVp: Mo/Mo, 28 kVp: Mo/Rh and 30 kVp: Rh/Rh, with polymethyl methacrylate (PMMA) 'tissue equivalent material' of thickness 20, 45 and 57 mm for each of three x-ray spectra at detector entrance air kerma in the range between ∼80.2 and 92.3 μGy. The noise equivalent quanta, NEQ(f), and detective quantum efficiencies, DQE(f), for the various spectral conditions were computed. In addition, dose dependence of NPS(f) and DQE(f) was studied at various detector entrance air kerma ranging from 9.4 to 169.7 μGy. A spatial resolution of about 10 cycles mm-1 was obtained at the 10% MTF(f) level. A small increase in NEQ(f)was observed under higher energy spectral conditions while the DQE(f) decreased marginally. For a given spectrum, increasing PMMA filtration produced negligible change in DQE(f). The estimated DQE values at zero frequency were in the range between 0.45 and 0.55 under the conditions investigated in this study.

Original languageEnglish (US)
Pages (from-to)3957-3969
Number of pages13
JournalPhysics in medicine and biology
Issue number17
StatePublished - Sep 7 2005

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging


Dive into the research topics of 'High-resolution imager for digital mammography: Physical characterization of a prototype sensor'. Together they form a unique fingerprint.

Cite this