High-resolution computed tomography of the normal rat nephrogram

Mohammad Ali Kujoory, Bruce J. Hillman, Harrison H. Barrett

Research output: Contribution to journalArticlepeer-review

27 Scopus citations


This study describes a unique, film-recorded computed tomography (CT) system and its use in studying contrast flow between anatomic compartments of the rat kidney. The CT apparatus, composed of a microfocal spot tube, rotating animal carrier, film-cassette translator, and control electronics, was used to expose “sinograms” of 3:1 magnification through the kidneys of normal rats prior to and 2, 15, 30, 60, and 120 minutes after intravenous contrast injection. Microdensitometry and computer reconstruction resulted in CT images representing 1-mm thick coronal sections with lateral resolution of 150 mm. With this novel technique of ultrahigh- resolution CT, temporal alterations in absorption coefficient of cortical and medullary nephrographic components were depicted for contrast flow study in our small animal model.

Original languageEnglish (US)
Pages (from-to)148-154
Number of pages7
JournalInvestigative Radiology
Issue number2
StatePublished - 1980


  • High-resolution film-recorded CT
  • Magnification CT
  • Rat experimental model
  • Renal contrast flow

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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