High-fat diet induces hepatic insulin resistance and impairment of synaptic plasticity

Agriculture & Biology

• neuroplasticity 100%
• insulin resistance 84%
• high fat diet 73%
• liver 40%
• insulin 26%
• brain 26%
• mitogen-activated protein kinase 24%
• fasting 14%
• hepatocytes 13%
• phosphorylation 13%
• mice 13%
• inactivation 12%
• insulin receptors 10%
• electrophysiology 10%
• glucose tolerance 10%
• glucose transporters 10%
• body weight 9%
• hippocampus 8%
• obesity 7%
• biogenesis 7%
• blood glucose 7%
• oxygen consumption 7%
• learning 6%
• inflammation 6%
• triacylglycerols 6%
• plasma membrane 5%

Medicine & Life Sciences

• High Fat Diet 68%
• Neuronal Plasticity 65%
• Insulin Resistance 56%
• Liver 35%
• Insulin 20%
• Long-Term Potentiation 17%
• Brain 14%
• Hepatocytes 12%
• Fasting 12%
• Body Weight 10%
• Phosphorylation 10%
• Insulin Receptor Substrate Proteins 9%
• Organelle Biogenesis 9%
• Glucose 9%
• Facilitative Glucose Transport Proteins 8%
• Electrophysiology 8%
• MAP Kinase Signaling System 8%
• p38 Mitogen-Activated Protein Kinases 7%
• Oxygen Consumption 7%
• Inbred C57BL Mouse 7%
• Blood Glucose 6%
• Theoretical Models 6%
• Triglycerides 6%
• Hippocampus 6%
• Fats 5%
• Learning 5%
• Memory 5%
• Cell Membrane 5%
• Obesity 5%
• Diet 5%

Chemical Compounds

• Plastic Property 79%
• Insulin Derivative 70%
• Resistance 43%
• Glucose 30%
• Plasma 25%
• Weight 14%
• Triglyceride 14%
• Fat 13%
• Dioxygen 6%