Herpes virus replication

Paul E. Boehmer; Amitabh V. Nimonkar

doi:10.1080/1521654031000070645

Herpes virus replication

Paul E. Boehmer, Amitabh V. Nimonkar

Research output: Contribution to journal › Review article › peer-review

92 Scopus citations

Abstract

Herpesviruses are large double stranded DNA animal viruses with the distinguishing ability to establish latent, life-long infections. To date, eight human herpesviruses that exhibit distinct biological and corresponding pathological/clinical properties have been identified. During their life cycles, herpesviruses execute an intricate chain of events geared towards optimizing their replication. This sets an interesting paradigm to study fundamental biological processes. This review summarizes recent developments in herpesvirus research with emphasis on genome transactions, particularly with respect to the prototypic herpes simplex virus type-1.

Original language	English (US)
Pages (from-to)	13-22
Number of pages	10
Journal	IUBMB Life
Volume	55
Issue number	1
DOIs	https://doi.org/10.1080/1521654031000070645
State	Published - Jan 1 2003
Externally published	Yes

Keywords

Gene expression
Herpes virus
Initiation
Latency
Lytic replication
Recombination

ASJC Scopus subject areas

Biochemistry
Molecular Biology
Genetics
Clinical Biochemistry
Cell Biology

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10.1080/1521654031000070645

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AU - Nimonkar, Amitabh V.

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AB - Herpesviruses are large double stranded DNA animal viruses with the distinguishing ability to establish latent, life-long infections. To date, eight human herpesviruses that exhibit distinct biological and corresponding pathological/clinical properties have been identified. During their life cycles, herpesviruses execute an intricate chain of events geared towards optimizing their replication. This sets an interesting paradigm to study fundamental biological processes. This review summarizes recent developments in herpesvirus research with emphasis on genome transactions, particularly with respect to the prototypic herpes simplex virus type-1.

KW - Gene expression

KW - Herpes virus

KW - Initiation

KW - Latency

KW - Lytic replication

KW - Recombination

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Herpes virus replication

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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