Hepatic toxicity of Vitamin A and synthetic retinoids

MICHAEL B. FALLON; JAMES L. BOYER

doi:10.1111/j.1440-1746.1990.tb01635.x

Hepatic toxicity of Vitamin A and synthetic retinoids

MICHAEL B. FALLON, JAMES L. BOYER

Research output: Contribution to journal › Article › peer-review

39 Scopus citations

Abstract

Vitamin A and synthetic retinoids have recently been used increasingly in a variety of health related concerns. Hepatic toxicity is an uncommon but serious side‐effect of several Vitamin A derivatives which may lead to cirrhosis. This review will focus on the clinical and pathologic findings of hepatic involvement in chronic hypervitaminosis A and on the evidence concerning the potential hepatotoxicity of currently available synthetic retinoids.

Original language	English (US)
Pages (from-to)	334-342
Number of pages	9
Journal	Journal of Gastroenterology and Hepatology
Volume	5
Issue number	3
DOIs	https://doi.org/10.1111/j.1440-1746.1990.tb01635.x
State	Published - Jun 1990
Externally published	Yes

Keywords

Key words:
Vitamin A.
etretinate
isotretinoin
liver
retinol
synthetic retinoids

ASJC Scopus subject areas

Hepatology
Gastroenterology

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10.1111/j.1440-1746.1990.tb01635.x

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abstract = "Vitamin A and synthetic retinoids have recently been used increasingly in a variety of health related concerns. Hepatic toxicity is an uncommon but serious side‐effect of several Vitamin A derivatives which may lead to cirrhosis. This review will focus on the clinical and pathologic findings of hepatic involvement in chronic hypervitaminosis A and on the evidence concerning the potential hepatotoxicity of currently available synthetic retinoids.",

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AU - BOYER, JAMES L.

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AB - Vitamin A and synthetic retinoids have recently been used increasingly in a variety of health related concerns. Hepatic toxicity is an uncommon but serious side‐effect of several Vitamin A derivatives which may lead to cirrhosis. This review will focus on the clinical and pathologic findings of hepatic involvement in chronic hypervitaminosis A and on the evidence concerning the potential hepatotoxicity of currently available synthetic retinoids.

KW - Key words:

KW - Vitamin A.

KW - etretinate

KW - isotretinoin

KW - liver

KW - retinol

KW - synthetic retinoids

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ER -

Hepatic toxicity of Vitamin A and synthetic retinoids

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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