Hemolysis due to Chemical Contamination of Clinical Perfusion Apparatus

Douglas F. Larson; Bruce Mayall; Robert M. Anderson

doi:10.1016/S0003-4975(10)64146-X

Hemolysis due to Chemical Contamination of Clinical Perfusion Apparatus

Douglas F. Larson, Bruce Mayall, Robert M. Anderson

Surgery

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

A chemical contaminant found on the interior surface of the extracorporeal apparatus manufactured by the William Harvey Corporation was believed to have caused severe hematuria in 2 children. The biological activity of the contaminant was tested by mixing 50 ml of whole blood in contaminated cardiotomies; after 5 minutes of exposure lysis of one-sixth of the red blood cells was found. This hemolytic agent was concluded to be bisphenol A dissolved in an organic solvent, but the mechanism of contamination was never found.

Original language	English (US)
Pages (from-to)	374-375
Number of pages	2
Journal	Annals of Thoracic Surgery
Volume	23
Issue number	4
DOIs	https://doi.org/10.1016/S0003-4975(10)64146-X
State	Published - 1977

ASJC Scopus subject areas

Surgery
Pulmonary and Respiratory Medicine
Cardiology and Cardiovascular Medicine

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abstract = "A chemical contaminant found on the interior surface of the extracorporeal apparatus manufactured by the William Harvey Corporation was believed to have caused severe hematuria in 2 children. The biological activity of the contaminant was tested by mixing 50 ml of whole blood in contaminated cardiotomies; after 5 minutes of exposure lysis of one-sixth of the red blood cells was found. This hemolytic agent was concluded to be bisphenol A dissolved in an organic solvent, but the mechanism of contamination was never found.",

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AU - Larson, Douglas F.

AU - Mayall, Bruce

AU - Anderson, Robert M.

PY - 1977

Y1 - 1977

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AB - A chemical contaminant found on the interior surface of the extracorporeal apparatus manufactured by the William Harvey Corporation was believed to have caused severe hematuria in 2 children. The biological activity of the contaminant was tested by mixing 50 ml of whole blood in contaminated cardiotomies; after 5 minutes of exposure lysis of one-sixth of the red blood cells was found. This hemolytic agent was concluded to be bisphenol A dissolved in an organic solvent, but the mechanism of contamination was never found.

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ER -

Hemolysis due to Chemical Contamination of Clinical Perfusion Apparatus

Abstract

ASJC Scopus subject areas

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