Hantavirus pulmonary syndrome complicating pregnancy

George J. Gilson, James A. Maciulla, Bobby G. Nevils, Luis E. Izquierdo, Molly S. Chatterjee, Luis B. Curet

Research output: Contribution to journalArticlepeer-review

17 Scopus citations


OBJECTIVE: The purpose of this report is to bring to the attention of obstetric care providers the occurrence in pregnancy of a threatening pulmonary syndrome caused by hantavirus infection. STUDY DESIGN: Two recent cases of hantavirus pneumonitis in pregnancy, one complicated by adult respiratory distress syndrome, are presented. The clinical characteristics and epidemiology of the illness, which has now been reported in 12 western states, are detailed. RESULTS: Hantavirus pulmonary syndrome is characterized by pneumonitis, often progressing to adult respiratory distress syndrome, which is accompanied by thrombocytopenia, lactacidemia, and leukocytosis with a marked left shift. Severe hypoxemia and lactacidemia were associated with a poor perinatal outcome. CONCLUSION: The hantavirus pulmonary syndrome occurring during pregnancy may be life-threatening and may result in fetal hypoxemic damage.

Original languageEnglish (US)
Pages (from-to)550-554
Number of pages5
JournalAmerican journal of obstetrics and gynecology
Issue number2
StatePublished - Aug 1994
Externally publishedYes


  • Hantavirus
  • adult respiratory distress syndrome
  • pregnancy

ASJC Scopus subject areas

  • Obstetrics and Gynecology


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