Hairy cell leukemia: Association with disseminated atypical mycobacterial infection

Robert A. Weinstein, Harvey M. Golomb, Gerald Grumet, Edward Gelmann, Geraldine P. Schechter

Research output: Contribution to journalArticlepeer-review

50 Scopus citations

Abstract

The cases of four patients with hairy cell leukemia and disseminated atypical mycobacterial infection (three with M. kansasii and one with M. intracellulare) are reported. These four patients were from a population of 38 patients with hairy cell leukemia evaluated at three institutions; there was an incidence figure of 10.5%. Despite infection with very drug‐resistant strains, two patients showed marked clinical improvement following aggressive multiple drug therapy. Such infection should be suspected in a patient with hairy cell leukemia who has persistent fever without an obvious source. Tissue biopsy usually led to diagnosis; urine cultures were also positive in two patients.

Original languageEnglish (US)
Pages (from-to)380-383
Number of pages4
JournalCancer
Volume48
Issue number2
DOIs
StatePublished - Jul 15 1981
Externally publishedYes

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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