TY - JOUR
T1 - Hairy cell leukemia
T2 - Association with disseminated atypical mycobacterial infection
AU - Weinstein, Robert A.
AU - Golomb, Harvey M.
AU - Grumet, Gerald
AU - Gelmann, Edward
AU - Schechter, Geraldine P.
PY - 1981/7/15
Y1 - 1981/7/15
N2 - The cases of four patients with hairy cell leukemia and disseminated atypical mycobacterial infection (three with M. kansasii and one with M. intracellulare) are reported. These four patients were from a population of 38 patients with hairy cell leukemia evaluated at three institutions; there was an incidence figure of 10.5%. Despite infection with very drug‐resistant strains, two patients showed marked clinical improvement following aggressive multiple drug therapy. Such infection should be suspected in a patient with hairy cell leukemia who has persistent fever without an obvious source. Tissue biopsy usually led to diagnosis; urine cultures were also positive in two patients.
AB - The cases of four patients with hairy cell leukemia and disseminated atypical mycobacterial infection (three with M. kansasii and one with M. intracellulare) are reported. These four patients were from a population of 38 patients with hairy cell leukemia evaluated at three institutions; there was an incidence figure of 10.5%. Despite infection with very drug‐resistant strains, two patients showed marked clinical improvement following aggressive multiple drug therapy. Such infection should be suspected in a patient with hairy cell leukemia who has persistent fever without an obvious source. Tissue biopsy usually led to diagnosis; urine cultures were also positive in two patients.
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U2 - 10.1002/1097-0142(19810715)48:2<380::AID-CNCR2820480226>3.0.CO;2-N
DO - 10.1002/1097-0142(19810715)48:2<380::AID-CNCR2820480226>3.0.CO;2-N
M3 - Article
C2 - 7237406
AN - SCOPUS:0019484063
SN - 0008-543X
VL - 48
SP - 380
EP - 383
JO - Cancer
JF - Cancer
IS - 2
ER -