TY - JOUR
T1 - Growth hormone deficiency in adults
T2 - Characteristics and response to growth hormone replacement
AU - Lieberman, S. A.
AU - Hoffman, A. R.
PY - 1996
Y1 - 1996
N2 - Despite adequate adrenal, gonadal, and thyroid hormone replacement, many adults with hypopituitarism have a recognizable syndrome of weakness and diminished sense of well-being, accompanied by alterations in metabolism and body composition, as well as increased mortality. Short-term treatment with human growth hormone improves many of these abnormalities, but a clear improvement in functional status has yet to be demonstrated. Until such an effect is shown, the use of growth hormone replacement in adults with hypopituitarism remains investigational.
AB - Despite adequate adrenal, gonadal, and thyroid hormone replacement, many adults with hypopituitarism have a recognizable syndrome of weakness and diminished sense of well-being, accompanied by alterations in metabolism and body composition, as well as increased mortality. Short-term treatment with human growth hormone improves many of these abnormalities, but a clear improvement in functional status has yet to be demonstrated. Until such an effect is shown, the use of growth hormone replacement in adults with hypopituitarism remains investigational.
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U2 - 10.1016/s0022-3476(96)70013-6
DO - 10.1016/s0022-3476(96)70013-6
M3 - Article
C2 - 8627472
AN - SCOPUS:0029915281
SN - 0022-3476
VL - 128
SP - S58-S60
JO - Journal of Pediatrics
JF - Journal of Pediatrics
IS - 5 II
ER -