TY - JOUR
T1 - Growth and Regression of the Germfree (Axenic) Thymus
AU - Wilson, Raphael
AU - Bealmear, Margaret
AU - Sobonya, Richard
N1 - Funding Information:
Supported by funds from Office of Naval Research, Nonr-1623(15).
PY - 1965/1
Y1 - 1965/1
N2 - Qualitatively, the growth patterns of the thymus of germfree and conventional mice are very similar, and the gross appearance is the same. In both groups of animals the period of thymus growth extends from birth to about 50 days, with accelerated growth during the first 2 weeks after birth, and peaks at about 15 days. Growth continues at a decelerated rate and regression of the thymus begins at about 50 days of age. A plateau is reached at about 200 days of age, but the thymus does not disappear completely. However, the thymus of conventional mice grows more rapidly and attains greater size than that of the germ-free mice.
AB - Qualitatively, the growth patterns of the thymus of germfree and conventional mice are very similar, and the gross appearance is the same. In both groups of animals the period of thymus growth extends from birth to about 50 days, with accelerated growth during the first 2 weeks after birth, and peaks at about 15 days. Growth continues at a decelerated rate and regression of the thymus begins at about 50 days of age. A plateau is reached at about 200 days of age, but the thymus does not disappear completely. However, the thymus of conventional mice grows more rapidly and attains greater size than that of the germ-free mice.
UR - https://www.scopus.com/pages/publications/78651185714
UR - https://www.scopus.com/inward/citedby.url?scp=78651185714&partnerID=8YFLogxK
U2 - 10.3181/00379727-118-29766
DO - 10.3181/00379727-118-29766
M3 - Article
C2 - 14254596
AN - SCOPUS:78651185714
SN - 0037-9727
VL - 118
SP - 97
EP - 99
JO - Proceedings of the Society for Experimental Biology and Medicine
JF - Proceedings of the Society for Experimental Biology and Medicine
IS - 1
ER -