Genetics for the general internist

Christina M. Laukaitis

doi:10.1016/j.amjmed.2011.07.034

Genetics for the general internist

Christina M. Laukaitis

Medicine

Research output: Contribution to journal › Review article › peer-review

1 Scopus citations

Abstract

The internist's goal is to determine a patient's disease risk and to implement preventative interventions. Genetic evaluation is a powerful risk assessment tool, and new interventions target previously untreatable genetic disorders. The purpose of this review is to educate the general internist about common genetic conditions affecting adult patients, with special emphasis on diagnoses with an effective intervention, including hereditary cancer syndromes and cardiovascular disorders. Basic tenets of genetic counseling, complex genetic disease, and management of adults with genetic diagnoses also are discussed.

Original language	English (US)
Pages (from-to)	7-13
Number of pages	7
Journal	American Journal of Medicine
Volume	125
Issue number	1
DOIs	https://doi.org/10.1016/j.amjmed.2011.07.034
State	Published - Jan 2012

Keywords

Alzheimer disease
Breast/ovarian cancer syndrome
Down syndrome
GINA
Genetics
Hereditary nonpolyposis colorectal cancer syndrome
Long QT syndrome
Lynch syndrome
Marfan syndrome
Neurofibromatosis 1
Venous thromboembolism

ASJC Scopus subject areas

Medicine(all)

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10.1016/j.amjmed.2011.07.034

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title = "Genetics for the general internist",

abstract = "The internist's goal is to determine a patient's disease risk and to implement preventative interventions. Genetic evaluation is a powerful risk assessment tool, and new interventions target previously untreatable genetic disorders. The purpose of this review is to educate the general internist about common genetic conditions affecting adult patients, with special emphasis on diagnoses with an effective intervention, including hereditary cancer syndromes and cardiovascular disorders. Basic tenets of genetic counseling, complex genetic disease, and management of adults with genetic diagnoses also are discussed.",

keywords = "Alzheimer disease, Breast/ovarian cancer syndrome, Down syndrome, GINA, Genetics, Hereditary nonpolyposis colorectal cancer syndrome, Long QT syndrome, Lynch syndrome, Marfan syndrome, Neurofibromatosis 1, Venous thromboembolism",

author = "Laukaitis, {Christina M.}",

note = "Funding Information: Funding: The author received support from the University of Arizona SPORE in GI Cancer ( CA95060 ) and a Cancer Center Support Grant ( CA023074 ). ",

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AB - The internist's goal is to determine a patient's disease risk and to implement preventative interventions. Genetic evaluation is a powerful risk assessment tool, and new interventions target previously untreatable genetic disorders. The purpose of this review is to educate the general internist about common genetic conditions affecting adult patients, with special emphasis on diagnoses with an effective intervention, including hereditary cancer syndromes and cardiovascular disorders. Basic tenets of genetic counseling, complex genetic disease, and management of adults with genetic diagnoses also are discussed.

KW - Alzheimer disease

KW - Breast/ovarian cancer syndrome

KW - Down syndrome

KW - GINA

KW - Genetics

KW - Hereditary nonpolyposis colorectal cancer syndrome

KW - Long QT syndrome

KW - Lynch syndrome

KW - Marfan syndrome

KW - Neurofibromatosis 1

KW - Venous thromboembolism

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DO - 10.1016/j.amjmed.2011.07.034

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Genetics for the general internist

Abstract

Keywords

ASJC Scopus subject areas

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