Asthma is a heterogeneous disease of related clinical phenotypes with a complex etiology based on genetic susceptibility and environmental influences. A primary aim of genetic studies in a common disease such as asthma is to identify a group of genetic variants that may interact with these environmental exposures to predict the risk for the development (susceptibility) or progression (severity) of asthma. Asthma susceptibility and severity are determined by a number of genetic variants that each contribute to the risk architecture.
|Original language||English (US)|
|Title of host publication||Clinical Asthma|
|Subtitle of host publication||Theory and Practice|
|Number of pages||8|
|State||Published - Jan 1 2014|
ASJC Scopus subject areas