Genetic analysis of bovine viral diarrhoea viruses from Australia

Timothy J. Mahony; Fiona M. McCarthy; Jennifer L. Gravel; Bruce Corney; Peter L. Young; Stefan Vilcek

doi:10.1016/j.vetmic.2004.10.024

Genetic analysis of bovine viral diarrhoea viruses from Australia

Timothy J. Mahony, Fiona M. McCarthy, Jennifer L. Gravel, Bruce Corney, Peter L. Young, Stefan Vilcek

Research output: Contribution to journal › Article › peer-review

64 Scopus citations

Abstract

Eighty-nine bovine viral diarrhoea viruses (BVDV) from Australia have been genetically typed by sequencing of the 5′ untranslated region (5′-UTR) and for selected isolates the N^pro region of the viral genome. Phylogenetic reconstructions indicated that all of the samples examined clustered within the BVDV type 1 genotype. Of the 11 previously described genetic groups of BVDV-1, 87 of the samples examined in this study clustered with the BVDV-1c, while two samples clustered with the BVDV-1a. Based on these analyses there appears to be limited genetic variation within the Australian BVDV field isolates. In addition, the phylogenetic reconstructions indicate that the clustering of Australian BVDV in the phylogenetic trees is not a result of geographic isolation.

Original language	English (US)
Pages (from-to)	1-6
Number of pages	6
Journal	Veterinary Microbiology
Volume	106
Issue number	1-2
DOIs	https://doi.org/10.1016/j.vetmic.2004.10.024
State	Published - Mar 20 2005
Externally published	Yes

Keywords

5′-UTR
Bovine viral diarrhoea virus
N
Phylogenetic reconstruction

ASJC Scopus subject areas

Microbiology
General Veterinary

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10.1016/j.vetmic.2004.10.024

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title = "Genetic analysis of bovine viral diarrhoea viruses from Australia",

abstract = "Eighty-nine bovine viral diarrhoea viruses (BVDV) from Australia have been genetically typed by sequencing of the 5′ untranslated region (5′-UTR) and for selected isolates the Npro region of the viral genome. Phylogenetic reconstructions indicated that all of the samples examined clustered within the BVDV type 1 genotype. Of the 11 previously described genetic groups of BVDV-1, 87 of the samples examined in this study clustered with the BVDV-1c, while two samples clustered with the BVDV-1a. Based on these analyses there appears to be limited genetic variation within the Australian BVDV field isolates. In addition, the phylogenetic reconstructions indicate that the clustering of Australian BVDV in the phylogenetic trees is not a result of geographic isolation.",

keywords = "5′-UTR, Bovine viral diarrhoea virus, N, Phylogenetic reconstruction",

author = "Mahony, {Timothy J.} and McCarthy, {Fiona M.} and Gravel, {Jennifer L.} and Bruce Corney and Young, {Peter L.} and Stefan Vilcek",

note = "Funding Information: The authors acknowledge Professor Colin Wilks of Victorian Institute for Animal Science and Dr. Jan Smith of James Cook University for provision of virus samples. The authors thank Mr Mark Kelly for performing the antigen capture ELISA analyses. The authors also thank Dr. Lee Taylor, Dr. Nigel Nichols and Dr. Steve Mathers for continued support and provision of viral samples. This work was supported by grant Flot.203 from Meat and Livestock Australia. S. V. was supported by VEGA grant (1/9014/02) and SP (51/0280803).",

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AU - McCarthy, Fiona M.

AU - Gravel, Jennifer L.

AU - Corney, Bruce

AU - Young, Peter L.

AU - Vilcek, Stefan

N1 - Funding Information: The authors acknowledge Professor Colin Wilks of Victorian Institute for Animal Science and Dr. Jan Smith of James Cook University for provision of virus samples. The authors thank Mr Mark Kelly for performing the antigen capture ELISA analyses. The authors also thank Dr. Lee Taylor, Dr. Nigel Nichols and Dr. Steve Mathers for continued support and provision of viral samples. This work was supported by grant Flot.203 from Meat and Livestock Australia. S. V. was supported by VEGA grant (1/9014/02) and SP (51/0280803).

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N2 - Eighty-nine bovine viral diarrhoea viruses (BVDV) from Australia have been genetically typed by sequencing of the 5′ untranslated region (5′-UTR) and for selected isolates the Npro region of the viral genome. Phylogenetic reconstructions indicated that all of the samples examined clustered within the BVDV type 1 genotype. Of the 11 previously described genetic groups of BVDV-1, 87 of the samples examined in this study clustered with the BVDV-1c, while two samples clustered with the BVDV-1a. Based on these analyses there appears to be limited genetic variation within the Australian BVDV field isolates. In addition, the phylogenetic reconstructions indicate that the clustering of Australian BVDV in the phylogenetic trees is not a result of geographic isolation.

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Genetic analysis of bovine viral diarrhoea viruses from Australia

Abstract

Keywords

ASJC Scopus subject areas

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