Gene ontology consortium: Going forward

Gene Ontology Consortium

doi:10.1093/nar/gku1179

Gene ontology consortium: Going forward

Gene Ontology Consortium

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2393 Scopus citations

Abstract

The Gene Ontology (GO; http://www.geneontology.org) is a community-based bioinformatics resource that supplies information about gene product function using ontologies to represent biological knowledge. Here we describe improvements and expansions to several branches of the ontology, as well as updates that have allowed us to more efficiently disseminate the GO and capture feedback from the research community. The Gene Ontology Consortium (GOC) has expanded areas of the ontology such as cilia-related terms, cell-cycle terms and multicellular organism processes. We have also implemented new tools for generating ontology terms based on a set of logical rules making use of templates, and we have made efforts to increase our use of logical definitions. The GOC has a new and improved web site summarizing new developments and documentation, serving as a portal to GO data. Users can perform GO enrichment analysis, and search the GO for terms, annotations to gene products, and associated metadata across multiple species using the all-new AmiGO2 browser. We encourage and welcome the input of the research community in all biological areas in our continued effort to improve the Gene Ontology.

Original language	English (US)
Pages (from-to)	D1049-D1056
Journal	Nucleic acids research
Volume	43
Issue number	D1
DOIs	https://doi.org/10.1093/nar/gku1179
State	Published - Jan 28 2015
Externally published	Yes

ASJC Scopus subject areas

Genetics

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10.1093/nar/gku1179

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@article{6096624759294dc38e49b9c10c82c781,

title = "Gene ontology consortium: Going forward",

abstract = "The Gene Ontology (GO; http://www.geneontology.org) is a community-based bioinformatics resource that supplies information about gene product function using ontologies to represent biological knowledge. Here we describe improvements and expansions to several branches of the ontology, as well as updates that have allowed us to more efficiently disseminate the GO and capture feedback from the research community. The Gene Ontology Consortium (GOC) has expanded areas of the ontology such as cilia-related terms, cell-cycle terms and multicellular organism processes. We have also implemented new tools for generating ontology terms based on a set of logical rules making use of templates, and we have made efforts to increase our use of logical definitions. The GOC has a new and improved web site summarizing new developments and documentation, serving as a portal to GO data. Users can perform GO enrichment analysis, and search the GO for terms, annotations to gene products, and associated metadata across multiple species using the all-new AmiGO2 browser. We encourage and welcome the input of the research community in all biological areas in our continued effort to improve the Gene Ontology.",

author = "{Gene Ontology Consortium} and Blake, {J. A.} and Christie, {K. R.} and Dolan, {M. E.} and Drabkin, {H. J.} and Hill, {D. P.} and L. Ni and D. Sitnikov and S. Burgess and T. Buza and C. Gresham and F. McCarthy and L. Pillai and H. Wang and S. Carbon and H. Dietze and Lewis, {S. E.} and Mungall, {C. J.} and Munoz-Torres, {M. C.} and M. Feuermann and P. Gaudet and S. Basu and Chisholm, {R. L.} and Dodson, {R. J.} and P. Fey and H. Mi and Thomas, {P. D.} and A. Muruganujan and S. Poudel and Hu, {J. C.} and Aleksander, {S. A.} and McIntosh, {B. K.} and Renfro, {D. P.} and Siegele, {D. A.} and H. Attrill and Brown, {N. H.} and S. Tweedie and J. Lomax and D. Osumi-Sutherland and H. Parkinson and P. Roncaglia and Lovering, {R. C.} and Talmud, {P. J.} and Humphries, {S. E.} and P. Denny and Campbell, {N. H.} and Foulger, {R. E.} and Chibucos, {M. C.} and Giglio, {M. Gwinn} and Chang, {H. Y.} and R. Finn",

note = "Publisher Copyright: {\textcopyright} The Author(s) 2014.",

year = "2015",

month = jan,

day = "28",

doi = "10.1093/nar/gku1179",

language = "English (US)",

volume = "43",

pages = "D1049--D1056",

journal = "Nucleic acids research",

issn = "0305-1048",

publisher = "Oxford University Press",

number = "D1",

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TY - JOUR

T1 - Gene ontology consortium

T2 - Going forward

AU - Gene Ontology Consortium

AU - Blake, J. A.

AU - Christie, K. R.

AU - Dolan, M. E.

AU - Drabkin, H. J.

AU - Hill, D. P.

AU - Ni, L.

AU - Sitnikov, D.

AU - Burgess, S.

AU - Buza, T.

AU - Gresham, C.

AU - McCarthy, F.

AU - Pillai, L.

AU - Wang, H.

AU - Carbon, S.

AU - Dietze, H.

AU - Lewis, S. E.

AU - Mungall, C. J.

AU - Munoz-Torres, M. C.

AU - Feuermann, M.

AU - Gaudet, P.

AU - Basu, S.

AU - Chisholm, R. L.

AU - Dodson, R. J.

AU - Fey, P.

AU - Mi, H.

AU - Thomas, P. D.

AU - Muruganujan, A.

AU - Poudel, S.

AU - Hu, J. C.

AU - Aleksander, S. A.

AU - McIntosh, B. K.

AU - Renfro, D. P.

AU - Siegele, D. A.

AU - Attrill, H.

AU - Brown, N. H.

AU - Tweedie, S.

AU - Lomax, J.

AU - Osumi-Sutherland, D.

AU - Parkinson, H.

AU - Roncaglia, P.

AU - Lovering, R. C.

AU - Talmud, P. J.

AU - Humphries, S. E.

AU - Denny, P.

AU - Campbell, N. H.

AU - Foulger, R. E.

AU - Chibucos, M. C.

AU - Giglio, M. Gwinn

AU - Chang, H. Y.

AU - Finn, R.

PY - 2015/1/28

Y1 - 2015/1/28

N2 - The Gene Ontology (GO; http://www.geneontology.org) is a community-based bioinformatics resource that supplies information about gene product function using ontologies to represent biological knowledge. Here we describe improvements and expansions to several branches of the ontology, as well as updates that have allowed us to more efficiently disseminate the GO and capture feedback from the research community. The Gene Ontology Consortium (GOC) has expanded areas of the ontology such as cilia-related terms, cell-cycle terms and multicellular organism processes. We have also implemented new tools for generating ontology terms based on a set of logical rules making use of templates, and we have made efforts to increase our use of logical definitions. The GOC has a new and improved web site summarizing new developments and documentation, serving as a portal to GO data. Users can perform GO enrichment analysis, and search the GO for terms, annotations to gene products, and associated metadata across multiple species using the all-new AmiGO2 browser. We encourage and welcome the input of the research community in all biological areas in our continued effort to improve the Gene Ontology.

AB - The Gene Ontology (GO; http://www.geneontology.org) is a community-based bioinformatics resource that supplies information about gene product function using ontologies to represent biological knowledge. Here we describe improvements and expansions to several branches of the ontology, as well as updates that have allowed us to more efficiently disseminate the GO and capture feedback from the research community. The Gene Ontology Consortium (GOC) has expanded areas of the ontology such as cilia-related terms, cell-cycle terms and multicellular organism processes. We have also implemented new tools for generating ontology terms based on a set of logical rules making use of templates, and we have made efforts to increase our use of logical definitions. The GOC has a new and improved web site summarizing new developments and documentation, serving as a portal to GO data. Users can perform GO enrichment analysis, and search the GO for terms, annotations to gene products, and associated metadata across multiple species using the all-new AmiGO2 browser. We encourage and welcome the input of the research community in all biological areas in our continued effort to improve the Gene Ontology.

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U2 - 10.1093/nar/gku1179

DO - 10.1093/nar/gku1179

M3 - Article

C2 - 25428369

AN - SCOPUS:84946735654

SN - 0305-1048

VL - 43

SP - D1049-D1056

JO - Nucleic acids research

JF - Nucleic acids research

IS - D1

ER -

Gene ontology consortium: Going forward

Abstract

ASJC Scopus subject areas

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