Gender and Stress

Robert J. Handa, C. J.Chung Wilson

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations


An increasing number of sex differences in neuroendocrine, autonomic, or behavioral responses to stress have been reported in the literature over the past several decades. Many studies used animal models to demonstrate hormonal and behavioral stress reactions, with the obvious advantage of being able to strictly control the type of stress administered and the previous history of stress experienced. Notwithstanding this advantage, studies have begun to examine gender differences in the human as well. The significance of gender differences in stress responses has become an important clinical issue given the number of pathologies associated with stressful life events. Ultimately, a better knowledge of the different strategies used by men and women to deal with stress and the influence of gonadal steroid hormones on these processes is important in the development of effective treatments for stress-related diseases.

Original languageEnglish (US)
Title of host publicationStress
Subtitle of host publicationPhysiology, Biochemistry, and Pathology Handbook of Stress Series, Volume 3
Number of pages12
ISBN (Electronic)9780128131466
ISBN (Print)9780128131473
StatePublished - Jan 1 2019


  • Activational CRH
  • Androgen
  • Estrogen
  • HPA
  • Organizational
  • Sex differences

ASJC Scopus subject areas

  • General Neuroscience


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