Abstract
We have isolated and characterized the developmental expression of Xenopus gdf16, a novel member of the growth/differentiation factor (gdf) gene family. The gdf16 gene encodes a pre-proprotein of 413 amino acids and a mature peptide of 122 amino acids. Gdf16 is most closely related to the zebrafish genes dynamo and radar, but exhibits a completely different expression pattern. Gene expression is detected at early tailbud (stage 25) in the first two epibranchial placodes and in a hindbrain-specific domain. As development proceeds, the gene is expressed in all the epibranchial placodes, the hindbrain, and the diencephalon. Copyright (C) 2000 Elsevier Science Ireland Ltd.
Original language | English (US) |
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Pages (from-to) | 279-282 |
Number of pages | 4 |
Journal | Mechanisms of Development |
Volume | 95 |
Issue number | 1-2 |
DOIs | |
State | Published - Jul 1 2000 |
Keywords
- Diencephalon
- Epibranchial placodes
- Gdf16
- Growth/differentiation factor
- Hindbrain
- TGF-β
ASJC Scopus subject areas
- Embryology
- Developmental Biology