TY - GEN
T1 - Gantry Design and Fabrication for a Stationary Adaptive SPECT System
AU - Richards, R. Garrett
AU - May, Micaehla
AU - Gardiner, Michael
AU - Bechetti, Geno
AU - Kalluri, Kesava S.
AU - Auer, Benjamin
AU - King, Michael A.
AU - Kuo, Phillip H.
AU - Furenlid, Lars R.
N1 - Publisher Copyright:
© 2021 IEEE.
PY - 2021
Y1 - 2021
N2 - Additive tungsten manufacturing opens up new design possibilities for stationary single-photon-emission computed tomography (SPECT) systems. We are developing AdaptiSPECT-C: an adaptive SPECT system designed for clinical whole brain imaging with a focus on drug discovery research for neurodegenerative diseases. The design comprises a 24-stationary camera configuration with actively controlled adjustable multi-pinhole apertures. That is, each of the five pinholes assigned to a camera can be switched between three different aperture diameters, enabling successive acquisition of image data from the same subject with different tradeoffs between spatial resolution and sensitivity, with both multiplexed and non-multiplexed projections, in a single session.We present here the mechanical integration for AdaptiSPECT-C, including fabrication and construction of the gantry, modular camera assemblies with collimators, and lead shielding structures. AdaptiSPECT-C's cameras each have an 18 cm x 18 cm light collection area, arranged to point at a common 21 cm spherical field of view with 0.54 nominal magnification. A highly modular camera and semi-kinematic mounting design has been established and validated that allows for future system iterations with even more capable detectors and collimation strategies. By managing a balance of systems-level fabrication and assembly tolerances, AdaptiSPECT-C can be constructed efficiently without specialized expertise and is easy to service with a high degree of repeatability between successive camera installations.
AB - Additive tungsten manufacturing opens up new design possibilities for stationary single-photon-emission computed tomography (SPECT) systems. We are developing AdaptiSPECT-C: an adaptive SPECT system designed for clinical whole brain imaging with a focus on drug discovery research for neurodegenerative diseases. The design comprises a 24-stationary camera configuration with actively controlled adjustable multi-pinhole apertures. That is, each of the five pinholes assigned to a camera can be switched between three different aperture diameters, enabling successive acquisition of image data from the same subject with different tradeoffs between spatial resolution and sensitivity, with both multiplexed and non-multiplexed projections, in a single session.We present here the mechanical integration for AdaptiSPECT-C, including fabrication and construction of the gantry, modular camera assemblies with collimators, and lead shielding structures. AdaptiSPECT-C's cameras each have an 18 cm x 18 cm light collection area, arranged to point at a common 21 cm spherical field of view with 0.54 nominal magnification. A highly modular camera and semi-kinematic mounting design has been established and validated that allows for future system iterations with even more capable detectors and collimation strategies. By managing a balance of systems-level fabrication and assembly tolerances, AdaptiSPECT-C can be constructed efficiently without specialized expertise and is easy to service with a high degree of repeatability between successive camera installations.
KW - gamma-ray detectors
KW - molecular imaging
KW - silicon radiation detectors
KW - single photon emission computed tomography
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U2 - 10.1109/NSS/MIC44867.2021.9875772
DO - 10.1109/NSS/MIC44867.2021.9875772
M3 - Conference contribution
AN - SCOPUS:85139168289
T3 - 2021 IEEE Nuclear Science Symposium and Medical Imaging Conference Record, NSS/MIC 2021 and 28th International Symposium on Room-Temperature Semiconductor Detectors, RTSD 2022
BT - 2021 IEEE Nuclear Science Symposium and Medical Imaging Conference Record, NSS/MIC 2021 and 28th International Symposium on Room-Temperature Semiconductor Detectors, RTSD 2022
A2 - Tomita, Hideki
A2 - Nakamura, Tatsuya
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 2021 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2021
Y2 - 16 October 2021 through 23 October 2021
ER -