Gamma-ray imaging using a CdZnTe pixel array and a high-resolution, parallel-hole collimator

G. A. Kastis; H. B. Barber; H. H. Barrett; S. J. Balzer; D. Lu; D. G. Marks; G. Stevenson; J. M. Woolfenden; M. Appleby; J. Tueller

doi:10.1109/23.914471

Gamma-ray imaging using a CdZnTe pixel array and a high-resolution, parallel-hole collimator

G. A. Kastis, H. B. Barber, H. H. Barrett, S. J. Balzer, D. Lu, D. G. Marks, G. Stevenson, J. M. Woolfenden, M. Appleby, J. Tueller

Medical Imaging

Research output: Contribution to journal › Article › peer-review

36 Scopus citations

Abstract

The poor performance of current parallel-hole collimators is an impediment to planar high-resolution gamma-ray imaging, even when high-resolution semiconductor detector arrays are available. High-resolution parallel-hole collimators are possible but have not been fabricated because conventional collimator construction techniques severely limit achievable bore size and septal thickness. We describe development and testing of a high-resolution collimator with 4096 260-μm square bores and 380 μm pitch, matched to our existing 2.5 cm × 2.5 cm hybrid 64×64 CdZnTe arrays with multiplexer readout. The collimator is a laminar composite of about 100 layers of W sheets produced by photolithography and has efficiency of 5×10^-5. We have demonstrated sub-millimeter spatial resolution at 140 keV in both phantom and animal imaging using this system. Images resolved individual vertebrae in the spine of a mouse and lymphatic channels and nodes in a rat. The collimator and semiconductor array could form a compact module for use in a wide variety of gamma-ray imaging systems.

Original language	English (US)
Pages (from-to)	1923-1927
Number of pages	5
Journal	IEEE Transactions on Nuclear Science
Volume	47
Issue number	6
DOIs	https://doi.org/10.1109/23.914471
State	Published - Dec 2000

ASJC Scopus subject areas

Nuclear and High Energy Physics
Nuclear Energy and Engineering
Electrical and Electronic Engineering

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@article{6fd8d8deace5483cbf58108a57bcf91a,

title = "Gamma-ray imaging using a CdZnTe pixel array and a high-resolution, parallel-hole collimator",

abstract = "The poor performance of current parallel-hole collimators is an impediment to planar high-resolution gamma-ray imaging, even when high-resolution semiconductor detector arrays are available. High-resolution parallel-hole collimators are possible but have not been fabricated because conventional collimator construction techniques severely limit achievable bore size and septal thickness. We describe development and testing of a high-resolution collimator with 4096 260-μm square bores and 380 μm pitch, matched to our existing 2.5 cm × 2.5 cm hybrid 64×64 CdZnTe arrays with multiplexer readout. The collimator is a laminar composite of about 100 layers of W sheets produced by photolithography and has efficiency of 5×10-5. We have demonstrated sub-millimeter spatial resolution at 140 keV in both phantom and animal imaging using this system. Images resolved individual vertebrae in the spine of a mouse and lymphatic channels and nodes in a rat. The collimator and semiconductor array could form a compact module for use in a wide variety of gamma-ray imaging systems.",

author = "Kastis, {G. A.} and Barber, {H. B.} and Barrett, {H. H.} and Balzer, {S. J.} and D. Lu and Marks, {D. G.} and G. Stevenson and Woolfenden, {J. M.} and M. Appleby and J. Tueller",

note = "Funding Information: The author would like to thank George McNeill and the technical staff of the Division of Nuclear Medicine of University Medical Center at the University of Arizona for support with the radiotracers. We would like to further thank Drs. A. Cress and L. Lee for providing the animals, G.D. Paine-Murrieta and K. Salam for helping with the animals, J. Sain for helping with the system, and Dr. A. Brill for suggesting the procedure for making very small point sources. The work was supported by National Institutes of Health Grant R01 CA75288 and P41 RR14304. George Kastis is a scholar of the {"}Alexander S. Onassis{"} Public Benefit Foundation under Group-T040.",

year = "2000",

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doi = "10.1109/23.914471",

language = "English (US)",

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T1 - Gamma-ray imaging using a CdZnTe pixel array and a high-resolution, parallel-hole collimator

AU - Kastis, G. A.

AU - Barber, H. B.

AU - Barrett, H. H.

AU - Balzer, S. J.

AU - Lu, D.

AU - Marks, D. G.

AU - Stevenson, G.

AU - Woolfenden, J. M.

AU - Appleby, M.

AU - Tueller, J.

N1 - Funding Information: The author would like to thank George McNeill and the technical staff of the Division of Nuclear Medicine of University Medical Center at the University of Arizona for support with the radiotracers. We would like to further thank Drs. A. Cress and L. Lee for providing the animals, G.D. Paine-Murrieta and K. Salam for helping with the animals, J. Sain for helping with the system, and Dr. A. Brill for suggesting the procedure for making very small point sources. The work was supported by National Institutes of Health Grant R01 CA75288 and P41 RR14304. George Kastis is a scholar of the "Alexander S. Onassis" Public Benefit Foundation under Group-T040.

PY - 2000/12

Y1 - 2000/12

N2 - The poor performance of current parallel-hole collimators is an impediment to planar high-resolution gamma-ray imaging, even when high-resolution semiconductor detector arrays are available. High-resolution parallel-hole collimators are possible but have not been fabricated because conventional collimator construction techniques severely limit achievable bore size and septal thickness. We describe development and testing of a high-resolution collimator with 4096 260-μm square bores and 380 μm pitch, matched to our existing 2.5 cm × 2.5 cm hybrid 64×64 CdZnTe arrays with multiplexer readout. The collimator is a laminar composite of about 100 layers of W sheets produced by photolithography and has efficiency of 5×10-5. We have demonstrated sub-millimeter spatial resolution at 140 keV in both phantom and animal imaging using this system. Images resolved individual vertebrae in the spine of a mouse and lymphatic channels and nodes in a rat. The collimator and semiconductor array could form a compact module for use in a wide variety of gamma-ray imaging systems.

AB - The poor performance of current parallel-hole collimators is an impediment to planar high-resolution gamma-ray imaging, even when high-resolution semiconductor detector arrays are available. High-resolution parallel-hole collimators are possible but have not been fabricated because conventional collimator construction techniques severely limit achievable bore size and septal thickness. We describe development and testing of a high-resolution collimator with 4096 260-μm square bores and 380 μm pitch, matched to our existing 2.5 cm × 2.5 cm hybrid 64×64 CdZnTe arrays with multiplexer readout. The collimator is a laminar composite of about 100 layers of W sheets produced by photolithography and has efficiency of 5×10-5. We have demonstrated sub-millimeter spatial resolution at 140 keV in both phantom and animal imaging using this system. Images resolved individual vertebrae in the spine of a mouse and lymphatic channels and nodes in a rat. The collimator and semiconductor array could form a compact module for use in a wide variety of gamma-ray imaging systems.

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Gamma-ray imaging using a CdZnTe pixel array and a high-resolution, parallel-hole collimator

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