Functionalization of ceramic liposomal nanoparticles, cerasomes, with antibodies

M. T. Stamm; Z. Zha; L. Jiang; Z. Dai; Y. Zohar

doi:10.1109/TRANSDUCERS.2011.5969803

Functionalization of ceramic liposomal nanoparticles, cerasomes, with antibodies

M. T. Stamm, Z. Zha, L. Jiang, Z. Dai, Y. Zohar

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Ceramic liposomal nanoparticles, cerasomes, are functionalized with antibodies on their surfaces that act as targeting ligands. This is achieved by using the siloxane network present on the cerasome surface as the foundation for chemical treatment processes previously developed for silicon surfaces. The bio-functionality and physical integrity of the cerasomes are characterized demonstrating successful immobilization of antibodies on the cerasome surface. The surface functionalization allows the cerasomes to deliver drugs to targeted cells expressing certain types of receptors with desired selectivity and specificity, which are not possible using standard liposomes.

Original language	English (US)
Title of host publication	2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11
Pages	1614-1617
Number of pages	4
DOIs	https://doi.org/10.1109/TRANSDUCERS.2011.5969803
State	Published - 2011
Event	2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11 - Beijing, China Duration: Jun 5 2011 → Jun 9 2011

Publication series

Name	2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11

Other

Other	2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11
Country/Territory	China
City	Beijing
Period	6/5/11 → 6/9/11

ASJC Scopus subject areas

Hardware and Architecture
Electrical and Electronic Engineering

Access to Document

10.1109/TRANSDUCERS.2011.5969803

Cite this

Stamm, M. T., Zha, Z., Jiang, L., Dai, Z., & Zohar, Y. (2011). Functionalization of ceramic liposomal nanoparticles, cerasomes, with antibodies. In 2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11 (pp. 1614-1617). Article 5969803 (2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11). https://doi.org/10.1109/TRANSDUCERS.2011.5969803

Functionalization of ceramic liposomal nanoparticles, cerasomes, with antibodies. / Stamm, M. T.; Zha, Z.; Jiang, L. et al.
2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11. 2011. p. 1614-1617 5969803 (2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Stamm, MT, Zha, Z, Jiang, L, Dai, Z & Zohar, Y 2011, Functionalization of ceramic liposomal nanoparticles, cerasomes, with antibodies. in 2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11., 5969803, 2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11, pp. 1614-1617, 2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11, Beijing, China, 6/5/11. https://doi.org/10.1109/TRANSDUCERS.2011.5969803

Stamm MT, Zha Z, Jiang L, Dai Z, Zohar Y. Functionalization of ceramic liposomal nanoparticles, cerasomes, with antibodies. In 2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11. 2011. p. 1614-1617. 5969803. (2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11). doi: 10.1109/TRANSDUCERS.2011.5969803

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abstract = "Ceramic liposomal nanoparticles, cerasomes, are functionalized with antibodies on their surfaces that act as targeting ligands. This is achieved by using the siloxane network present on the cerasome surface as the foundation for chemical treatment processes previously developed for silicon surfaces. The bio-functionality and physical integrity of the cerasomes are characterized demonstrating successful immobilization of antibodies on the cerasome surface. The surface functionalization allows the cerasomes to deliver drugs to targeted cells expressing certain types of receptors with desired selectivity and specificity, which are not possible using standard liposomes.",

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Functionalization of ceramic liposomal nanoparticles, cerasomes, with antibodies

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