Functional connectivity in auditory cortex using chronic, multichannel unit recordings

Ryan S. Clement; Russell S. Witte; Patrick J. Rousche; Daryl R. Kipke

doi:10.1016/S0925-2312(99)00023-5

Functional connectivity in auditory cortex using chronic, multichannel unit recordings

Ryan S. Clement, Russell S. Witte, Patrick J. Rousche, Daryl R. Kipke

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

Chronic, multichannel recordings provide a method for reliable detection and determination of long-term dynamic functional connectivity. Using chronically implanted multichannel electrode arrays, we simultaneously recorded 30-70 units in guinea pig auditory cortex in daily recording sessions for implant durations of six months. We examined stimulus response properties and correlation strengths in neuron pairs in four animals. Preliminary results from these 'snapshots' of functional connectivity suggest sparse functional connections among widely distributed neurons. Some of these functional connections were found to persist for several days. These results provide a framework upon which further investigations of functional dynamic connectivity can be developed.

Original language	English (US)
Pages (from-to)	347-354
Number of pages	8
Journal	Neurocomputing
Volume	26-27
DOIs	https://doi.org/10.1016/S0925-2312(99)00023-5
State	Published - Jun 1999
Externally published	Yes

Keywords

Auditory cortex
Connectivity
Correlation
Plasticity

ASJC Scopus subject areas

Computer Science Applications
Cognitive Neuroscience
Artificial Intelligence

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10.1016/S0925-2312(99)00023-5

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title = "Functional connectivity in auditory cortex using chronic, multichannel unit recordings",

abstract = "Chronic, multichannel recordings provide a method for reliable detection and determination of long-term dynamic functional connectivity. Using chronically implanted multichannel electrode arrays, we simultaneously recorded 30-70 units in guinea pig auditory cortex in daily recording sessions for implant durations of six months. We examined stimulus response properties and correlation strengths in neuron pairs in four animals. Preliminary results from these 'snapshots' of functional connectivity suggest sparse functional connections among widely distributed neurons. Some of these functional connections were found to persist for several days. These results provide a framework upon which further investigations of functional dynamic connectivity can be developed.",

keywords = "Auditory cortex, Connectivity, Correlation, Plasticity",

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year = "1999",

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T1 - Functional connectivity in auditory cortex using chronic, multichannel unit recordings

AU - Clement, Ryan S.

AU - Witte, Russell S.

AU - Rousche, Patrick J.

AU - Kipke, Daryl R.

PY - 1999/6

Y1 - 1999/6

N2 - Chronic, multichannel recordings provide a method for reliable detection and determination of long-term dynamic functional connectivity. Using chronically implanted multichannel electrode arrays, we simultaneously recorded 30-70 units in guinea pig auditory cortex in daily recording sessions for implant durations of six months. We examined stimulus response properties and correlation strengths in neuron pairs in four animals. Preliminary results from these 'snapshots' of functional connectivity suggest sparse functional connections among widely distributed neurons. Some of these functional connections were found to persist for several days. These results provide a framework upon which further investigations of functional dynamic connectivity can be developed.

AB - Chronic, multichannel recordings provide a method for reliable detection and determination of long-term dynamic functional connectivity. Using chronically implanted multichannel electrode arrays, we simultaneously recorded 30-70 units in guinea pig auditory cortex in daily recording sessions for implant durations of six months. We examined stimulus response properties and correlation strengths in neuron pairs in four animals. Preliminary results from these 'snapshots' of functional connectivity suggest sparse functional connections among widely distributed neurons. Some of these functional connections were found to persist for several days. These results provide a framework upon which further investigations of functional dynamic connectivity can be developed.

KW - Auditory cortex

KW - Connectivity

KW - Correlation

KW - Plasticity

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DO - 10.1016/S0925-2312(99)00023-5

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SN - 0925-2312

VL - 26-27

SP - 347

EP - 354

JO - Neurocomputing

JF - Neurocomputing

ER -

Functional connectivity in auditory cortex using chronic, multichannel unit recordings

Abstract

Keywords

ASJC Scopus subject areas

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