From quantal counts to mechanisms and systems: The past, present, and future of biometrics in environmental toxicology

A. John Bailer, Walter W. Piegorsch

Research output: Contribution to journalReview articlepeer-review

4 Scopus citations

Abstract

As appreciation for human impact on the environment has developed, so have the experimental systems and associated statistical tools that quantify this impact. Toxicological study in particular has grown in its complexity and its need for advanced statistical support. Within this perspective, we describe statistical practice in environmental toxicology and risk assessment. We present two case studies, one from mammalian toxicology and one from aquatic toxicology, that highlight the evolution of statistical practice in environmental toxicology.

Original languageEnglish (US)
Pages (from-to)327-336
Number of pages10
JournalBiometrics
Volume56
Issue number2
DOIs
StatePublished - Jun 2000
Externally publishedYes

Keywords

  • Aquatic toxicology
  • Concentration-response modeling
  • Dose-response modeling
  • Ecotoxicology
  • Environmental carcinogenesis
  • Environmental health
  • Environmental statistics
  • Environmetrics
  • Interdisciplinary collaboration
  • NOEC
  • NOEL
  • Potency estimation
  • Quantitative risk assessment
  • Response inhibition
  • Risk analysis
  • Stochastic modeling
  • Trend tests

ASJC Scopus subject areas

  • Statistics and Probability
  • General Biochemistry, Genetics and Molecular Biology
  • General Immunology and Microbiology
  • General Agricultural and Biological Sciences
  • Applied Mathematics

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