TY - JOUR
T1 - Frailty as a prognostic factor for the critically ill older adult trauma patients
AU - Hamidi, Mohammad
AU - Zeeshan, Muhammad
AU - Leon-Risemberg, Valeria
AU - Nikolich-Zugich, Janko
AU - Hanna, Kamil
AU - Kulvatunyou, Narong
AU - Saljuqi, Abdul Tawab
AU - Fain, Mindy
AU - Joseph, Bellal
N1 - Publisher Copyright:
© 2019 Elsevier Inc.
PY - 2019/9
Y1 - 2019/9
N2 - Background: Frailty is highly prevalent in the elderly and confers high risk for adverse outcomes. We aimed to assess the impact of frailty on critically ill older adult trauma patients. Methods: We analyzed the ACS-TQIP(2010–2014) including all critically-ill trauma patients ≥65y. The modified frailty index (mFI) was calculated. Following stratified into frail and non-frail, propensity score matching was performed. Our primary outcome measure was in-hospital complications. Secondary outcome measures included mortality and discharge disposition. Results: We identified 88,629 patients, of which 34,854 patients (frail: 17,427, non-frail: 17,427) were matched. Overall 14% died. Frail patients had higher rates of complications (34% vs. 18%, p < 0.001), mortality (18.1% vs. 9.7%, p < 0.001), and were more likely to be discharged to rehab/SNF (58.7% vs. 21.2% p < 0.001) compared to non-frail patients. Conclusion: critically-ill frail patients are more likely to have higher morbidity and mortality. Frailty can be used as an objective measure to identify high-risk patients.
AB - Background: Frailty is highly prevalent in the elderly and confers high risk for adverse outcomes. We aimed to assess the impact of frailty on critically ill older adult trauma patients. Methods: We analyzed the ACS-TQIP(2010–2014) including all critically-ill trauma patients ≥65y. The modified frailty index (mFI) was calculated. Following stratified into frail and non-frail, propensity score matching was performed. Our primary outcome measure was in-hospital complications. Secondary outcome measures included mortality and discharge disposition. Results: We identified 88,629 patients, of which 34,854 patients (frail: 17,427, non-frail: 17,427) were matched. Overall 14% died. Frail patients had higher rates of complications (34% vs. 18%, p < 0.001), mortality (18.1% vs. 9.7%, p < 0.001), and were more likely to be discharged to rehab/SNF (58.7% vs. 21.2% p < 0.001) compared to non-frail patients. Conclusion: critically-ill frail patients are more likely to have higher morbidity and mortality. Frailty can be used as an objective measure to identify high-risk patients.
KW - Complications
KW - ICU
KW - In-hospital
KW - Mortality
KW - Trauma
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U2 - 10.1016/j.amjsurg.2019.01.035
DO - 10.1016/j.amjsurg.2019.01.035
M3 - Article
C2 - 30833015
AN - SCOPUS:85062181595
SN - 0002-9610
VL - 218
SP - 484
EP - 489
JO - American journal of surgery
JF - American journal of surgery
IS - 3
ER -