TY - JOUR
T1 - Four years' experience with fibrin sealant in thoracic and cardiovascular surgery
AU - Matthew, Thomas L.
AU - Spotnitz, William D.
AU - Kron, Irving L.
AU - Daniel, Thomas M.
AU - Tribble, Curtis G.
AU - Nolan, Stanton P.
PY - 1990/7
Y1 - 1990/7
N2 - A single-donor fibrin sealant system was used in 689 thoracic and cardiovascular surgical procedures over the 4-year period between April 1, 1985, and March 31, 1989. An excellent overall success rate ( 646 689, 94% effective) was achieved with specific applications, including reduction of leakage of air ( 29 33, 88% effective), blood ( 595 634, 94% effective), and fluid ( 14 14, 100% effective), as well as positioning of anatomical structures such as coronary bypass grafts ( 8 8, 100% effective). Application methods included use of spray bottles ( 477 497, 96% effective), syringes ( 165 186, 89% effective), and a Silastic cannula through the flexible fiber-optic bronchoscope ( 4 6, 67% effective). The system was used in a wide variety of cardiac, pulmonary, esophageal, and vascular procedures to seal staple lines, suture lines, anastomoses, conduits, fistulas, and raw surfaces. No complications with this single-donor system secondary to blood-borne disease have been documented. Overall infection occurred at a nominal rate ( 16 689, 2%). Thus, fibrin sealant has been a useful tool to control the leakage of air, blood, and fluid during a wide variety of thoracic and cardiovascular procedures and may be of benefit to other surgeons.
AB - A single-donor fibrin sealant system was used in 689 thoracic and cardiovascular surgical procedures over the 4-year period between April 1, 1985, and March 31, 1989. An excellent overall success rate ( 646 689, 94% effective) was achieved with specific applications, including reduction of leakage of air ( 29 33, 88% effective), blood ( 595 634, 94% effective), and fluid ( 14 14, 100% effective), as well as positioning of anatomical structures such as coronary bypass grafts ( 8 8, 100% effective). Application methods included use of spray bottles ( 477 497, 96% effective), syringes ( 165 186, 89% effective), and a Silastic cannula through the flexible fiber-optic bronchoscope ( 4 6, 67% effective). The system was used in a wide variety of cardiac, pulmonary, esophageal, and vascular procedures to seal staple lines, suture lines, anastomoses, conduits, fistulas, and raw surfaces. No complications with this single-donor system secondary to blood-borne disease have been documented. Overall infection occurred at a nominal rate ( 16 689, 2%). Thus, fibrin sealant has been a useful tool to control the leakage of air, blood, and fluid during a wide variety of thoracic and cardiovascular procedures and may be of benefit to other surgeons.
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U2 - 10.1016/0003-4975(90)90080-P
DO - 10.1016/0003-4975(90)90080-P
M3 - Article
C2 - 2369228
AN - SCOPUS:0025302617
VL - 50
SP - 40
EP - 43
JO - Annals of Thoracic Surgery
JF - Annals of Thoracic Surgery
SN - 0003-4975
IS - 1
ER -