Four new 12-deoxyphorbol diesters from Croton californicus

Pedro I. Chavez; Shivanand D. Jolad; Joseph J. Hoffmann; Jack R. Cole

doi:10.1021/np50024a020

Four new 12-deoxyphorbol diesters from Croton californicus

Pedro I. Chavez, Shivanand D. Jolad, Joseph J. Hoffmann, Jack R. Cole

Pharmacy Practice and Science

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16 Scopus citations

Abstract

The petroleum ether and ethanol extracts of Croton californicus (Euphorbiaceae) yielded, upon further fractionation, a tlc single spot complex mixture. The resolution of this mixture by reverse phase hplc gave four new 12-deoxyphorbol-13,20-diesters (1–4) whose identities were established by spectral properties and by chemical transformations.

Original language	English (US)
Pages (from-to)	745-748
Number of pages	4
Journal	Journal Of Natural Products
Volume	45
Issue number	6
DOIs	https://doi.org/10.1021/np50024a020
State	Published - 1982

ASJC Scopus subject areas

Analytical Chemistry
Molecular Medicine
Pharmacology
Pharmaceutical Science
Drug Discovery
Complementary and alternative medicine
Organic Chemistry

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10.1021/np50024a020

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title = "Four new 12-deoxyphorbol diesters from Croton californicus",

abstract = "The petroleum ether and ethanol extracts of Croton californicus (Euphorbiaceae) yielded, upon further fractionation, a tlc single spot complex mixture. The resolution of this mixture by reverse phase hplc gave four new 12-deoxyphorbol-13,20-diesters (1–4) whose identities were established by spectral properties and by chemical transformations.",

author = "Chavez, \{Pedro I.\} and Jolad, \{Shivanand D.\} and Hoffmann, \{Joseph J.\} and Cole, \{Jack R.\}",

year = "1982",

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AU - Jolad, Shivanand D.

AU - Hoffmann, Joseph J.

AU - Cole, Jack R.

PY - 1982

Y1 - 1982

N2 - The petroleum ether and ethanol extracts of Croton californicus (Euphorbiaceae) yielded, upon further fractionation, a tlc single spot complex mixture. The resolution of this mixture by reverse phase hplc gave four new 12-deoxyphorbol-13,20-diesters (1–4) whose identities were established by spectral properties and by chemical transformations.

AB - The petroleum ether and ethanol extracts of Croton californicus (Euphorbiaceae) yielded, upon further fractionation, a tlc single spot complex mixture. The resolution of this mixture by reverse phase hplc gave four new 12-deoxyphorbol-13,20-diesters (1–4) whose identities were established by spectral properties and by chemical transformations.

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U2 - 10.1021/np50024a020

DO - 10.1021/np50024a020

M3 - Article

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JO - Journal Of Natural Products

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ER -

Four new 12-deoxyphorbol diesters from Croton californicus

Abstract

ASJC Scopus subject areas

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