Four new 12-deoxyphorbol diesters from Croton californicus

Pedro I. Chavez, Shivanand D. Jolad, Joseph J. Hoffmann, Jack R. Cole

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


The petroleum ether and ethanol extracts of Croton californicus (Euphorbiaceae) yielded, upon further fractionation, a tlc single spot complex mixture. The resolution of this mixture by reverse phase hplc gave four new 12-deoxyphorbol-13,20-diesters (1–4) whose identities were established by spectral properties and by chemical transformations.

Original languageEnglish (US)
Pages (from-to)745-748
Number of pages4
JournalJournal Of Natural Products
Issue number6
StatePublished - 1982

ASJC Scopus subject areas

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry


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