Fluorescent probes for the detection of hydrogen sulfide in biological systems

Weimin Xuan, Chunquan Sheng, Yanting Cao, Wenhan He, Wei Wang

Research output: Contribution to journalArticlepeer-review

270 Scopus citations


Detective work: Three highly sensitive and selective fluorescent probes for the detection of H 2S have been developed. Two of the probes detect H 2S by the reduction of an azide moiety to an amine group, which changes the probes into their fluorescent forms and generates a fluorescent signal. In the third method, the fluorescent signal is created by using H 2S as a nucleophile in a reaction that unmasks fluorescein.

Original languageEnglish (US)
Pages (from-to)2282-2284
Number of pages3
JournalAngewandte Chemie - International Edition
Issue number10
StatePublished - Mar 5 2012
Externally publishedYes


  • azides
  • fluorescein
  • fluorescent probes
  • hydrogen sulfide
  • rhodamines

ASJC Scopus subject areas

  • Catalysis
  • General Chemistry


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