Fluorescent probes for the detection of hydrogen sulfide in biological systems

Weimin Xuan; Chunquan Sheng; Yanting Cao; Wenhan He; Wei Wang

doi:10.1002/anie.201107025

Fluorescent probes for the detection of hydrogen sulfide in biological systems

Weimin Xuan, Chunquan Sheng, Yanting Cao, Wenhan He, Wei Wang

Research output: Contribution to journal › Article › peer-review

276 Scopus citations

Abstract

Detective work: Three highly sensitive and selective fluorescent probes for the detection of H ₂S have been developed. Two of the probes detect H ₂S by the reduction of an azide moiety to an amine group, which changes the probes into their fluorescent forms and generates a fluorescent signal. In the third method, the fluorescent signal is created by using H ₂S as a nucleophile in a reaction that unmasks fluorescein.

Original language	English (US)
Pages (from-to)	2282-2284
Number of pages	3
Journal	Angewandte Chemie - International Edition
Volume	51
Issue number	10
DOIs	https://doi.org/10.1002/anie.201107025
State	Published - Mar 5 2012
Externally published	Yes

Keywords

azides
fluorescein
fluorescent probes
hydrogen sulfide
rhodamines

ASJC Scopus subject areas

Catalysis
General Chemistry

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10.1002/anie.201107025

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abstract = "Detective work: Three highly sensitive and selective fluorescent probes for the detection of H 2S have been developed. Two of the probes detect H 2S by the reduction of an azide moiety to an amine group, which changes the probes into their fluorescent forms and generates a fluorescent signal. In the third method, the fluorescent signal is created by using H 2S as a nucleophile in a reaction that unmasks fluorescein.",

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AU - Sheng, Chunquan

AU - Cao, Yanting

AU - He, Wenhan

AU - Wang, Wei

PY - 2012/3/5

Y1 - 2012/3/5

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AB - Detective work: Three highly sensitive and selective fluorescent probes for the detection of H 2S have been developed. Two of the probes detect H 2S by the reduction of an azide moiety to an amine group, which changes the probes into their fluorescent forms and generates a fluorescent signal. In the third method, the fluorescent signal is created by using H 2S as a nucleophile in a reaction that unmasks fluorescein.

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KW - fluorescein

KW - fluorescent probes

KW - hydrogen sulfide

KW - rhodamines

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Fluorescent probes for the detection of hydrogen sulfide in biological systems

Abstract

Keywords

ASJC Scopus subject areas

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