Fluorescent and lanthanide labeling for ligand screens, assays, and imaging.

Jatinder S. Josan; Channa R. De Silva; Byunghee Yoo; Ronald M. Lynch; Mark D. Pagel; Josef Vagner; Victor J. Hruby

doi:10.1007/978-1-61779-012-6_6

Fluorescent and lanthanide labeling for ligand screens, assays, and imaging.

Jatinder S. Josan, Channa R. De Silva, Byunghee Yoo, Ronald M. Lynch, Mark D. Pagel, Josef Vagner, Victor J. Hruby

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

The use of fluorescent (or luminescent) and metal contrast agents in high-throughput screens, in vitro assays, and molecular imaging procedures has rapidly expanded in recent years. Here we describe the development and utility of high-affinity ligands for cancer theranostics and other in vitro screening -studies. In this context, we also illustrate the syntheses and use of heteromultivalent ligands as targeted imaging agents.

Original language	English (US)
Pages (from-to)	89-126
Number of pages	38
Journal	Methods in molecular biology (Clifton, N.J.)
Volume	716
DOIs	https://doi.org/10.1007/978-1-61779-012-6_6
State	Published - 2011

ASJC Scopus subject areas

Molecular Biology
Genetics

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10.1007/978-1-61779-012-6_6

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AU - Yoo, Byunghee

AU - Lynch, Ronald M.

AU - Pagel, Mark D.

AU - Vagner, Josef

AU - Hruby, Victor J.

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ER -

Fluorescent and lanthanide labeling for ligand screens, assays, and imaging.

Abstract

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