TY - JOUR
T1 - Five new isocoumarins from Sonoran desert plant-associated fungal strains Paraphaeosphaeria quadriseptata and Chaetomium chiversii
AU - Wijeratne, E. M.Kithsiri
AU - Paranagama, Priyani A.
AU - Gunatilaka, A. A.Leslie
N1 - Funding Information:
Financial support from the National Cancer Institute (Grant R01 CA 90265) and Arizona Biomedical Research Commission (Grant 9014) is gratefully acknowledged. P.A.P. thanks the Council for International Exchange of Scholars for a Fulbright fellowship and University of Kelaniya, Sri Lanka, for granting leave of absence. We thank Drs. Stan Faeth (Arizona State University) and Hans D. VanEtten (The University of Arizona) for providing the fungal strains used in this study.
PY - 2006/9/4
Y1 - 2006/9/4
N2 - Five new isocoumarins, paraphaeosphaerins A-C and chaetochiversins A and B, biogenetically related to monocillin I and radicicol, have been isolated from solid agar cultures of Paraphaeosphaeria quadriseptata and Chaetomium chiversii, two fungal strains living in association with the Sonoran desert plants, Opuntia leptocaulis and Ephedra fasciculata, respectively. A new chroman-4-one, aposphaerin C, was also isolated from P. quadriseptata. Their structures and stereochemistry were elucidated using a combination of 1H and 13C homo- and hetero-nuclear 2D NMR techniques, 1H NMR analysis of Mosher's esters, and chemical correlations.
AB - Five new isocoumarins, paraphaeosphaerins A-C and chaetochiversins A and B, biogenetically related to monocillin I and radicicol, have been isolated from solid agar cultures of Paraphaeosphaeria quadriseptata and Chaetomium chiversii, two fungal strains living in association with the Sonoran desert plants, Opuntia leptocaulis and Ephedra fasciculata, respectively. A new chroman-4-one, aposphaerin C, was also isolated from P. quadriseptata. Their structures and stereochemistry were elucidated using a combination of 1H and 13C homo- and hetero-nuclear 2D NMR techniques, 1H NMR analysis of Mosher's esters, and chemical correlations.
KW - Aposphaerin C
KW - Chaetochiversins
KW - Chaetomium chiversii
KW - Endophytic and rhizosphere fungi
KW - Paraphaeosphaeria quadriseptata
KW - Paraphaeosphaerins
KW - Structure elucidation
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U2 - 10.1016/j.tet.2006.06.089
DO - 10.1016/j.tet.2006.06.089
M3 - Article
AN - SCOPUS:33746316567
SN - 0040-4020
VL - 62
SP - 8439
EP - 8446
JO - Tetrahedron
JF - Tetrahedron
IS - 36
ER -