First World Consensus Conference on pancreas transplantation: Part II – recommendations

Ugo Boggi, Fabio Vistoli, Axel Andres, Helmut P. Arbogast, Lionel Badet, Walter Baronti, Stephen T. Bartlett, Enrico Benedetti, Julien Branchereau, George W. Burke, Fanny Buron, Rossana Caldara, Massimo Cardillo, Daniel Casanova, Federica Cipriani, Matthew Cooper, Adamasco Cupisti, Josè Davide, Cinthia Drachenberg, Eelco J.P. de KoningGiuseppe Maria Ettorre, Laureano Fernandez Cruz, Jonathan A. Fridell, Peter J. Friend, Lucrezia Furian, Osama A. Gaber, Angelika C. Gruessner, Rainer W.G. Gruessner, Jenny E. Gunton, Duck Jong Han, Sara Iacopi, Emanuele Federico Kauffmann, Dixon Kaufman, Takashi Kenmochi, Hussein A. Khambalia, Quirino Lai, Robert M. Langer, Paola Maffi, Lorella Marselli, Francesco Menichetti, Mario Miccoli, Shruti Mittal, Emmanuel Morelon, Niccolò Napoli, Flavia Neri, Jose Oberholzer, Jon S. Odorico, Robert Öllinger, Gabriel Oniscu, Giuseppe Orlando, Monica Ortenzi, Marcelo Perosa, Vittorio Grazio Perrone, Henry Pleass, Robert R. Redfield, Claudio Ricci, Paolo Rigotti, R. Paul Robertson, Lainie F. Ross, Massimo Rossi, Frantisek Saudek, Joseph R. Scalea, Peter Schenker, Antonio Secchi, Carlo Socci, Donzilia Sousa Silva, Jean Paul Squifflet, Peter G. Stock, Robert J. Stratta, Chiara Terrenzio, Pablo Uva, Christopher J.E. Watson, Steven A. White, Piero Marchetti, Raja Kandaswamy, Thierry Berney

Research output: Contribution to journalArticlepeer-review

36 Scopus citations


The First World Consensus Conference on Pancreas Transplantation provided 49 jury deliberations regarding the impact of pancreas transplantation on the treatment of diabetic patients, and 110 experts’ recommendations for the practice of pancreas transplantation. The main message from this consensus conference is that both simultaneous pancreas-kidney transplantation (SPK) and pancreas transplantation alone can improve long-term patient survival, and all types of pancreas transplantation dramatically improve the quality of life of recipients. Pancreas transplantation may also improve the course of chronic complications of diabetes, depending on their severity. Therefore, the advantages of pancreas transplantation appear to clearly surpass potential disadvantages. Pancreas after kidney transplantation increases the risk of mortality only in the early period after transplantation, but is associated with improved life expectancy thereafter. Additionally, preemptive SPK, when compared to SPK performed in patients undergoing dialysis, appears to be associated with improved outcomes. Time on dialysis has negative prognostic implications in SPK recipients. Increased long-term survival, improvement in the course of diabetic complications, and amelioration of quality of life justify preferential allocation of kidney grafts to SPK recipients. Audience discussions and live voting are available online at the following URL address:

Original languageEnglish (US)
Pages (from-to)17-59
Number of pages43
JournalAmerican Journal of Transplantation
Issue numberS3
StatePublished - Sep 2021


  • clinical research/practice
  • diabetes
  • pancreas/simultaneous pancreas-kidney transplantation
  • survey

ASJC Scopus subject areas

  • Immunology and Allergy
  • Transplantation
  • Pharmacology (medical)


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