TY - GEN
T1 - Field-based multiplex and quantitative assay platforms for diagnostics
AU - Venkatasubbarao, Srivatsa
AU - Dixon, C. Edward
AU - Chipman, Russell
AU - Scherer, Axel
AU - Beshay, Manal
AU - Kempen, Lothar U.
AU - Chandra Sekhar, Jai Ganesh
AU - Yan, Hong
AU - Puccio, Ava
AU - Okonkwo, David
AU - McClain, Stephen
AU - Gilbert, Noah
AU - Vyawahare, Saurabh
PY - 2011
Y1 - 2011
N2 - The U.S. military has a continued interest in the development of handheld, field-usable sensors and test kits for a variety of diagnostic applications, such as traumatic brain injury (TBI) and infectious diseases. Field-use presents unique challenges for biosensor design, both for the readout unit and for the biological assay platform. We have developed robust biosensor devices that offer ultra-high sensitivity and also meet field-use needs. The systems under development include a multiplexed quantitative lateral flow test strip for TBI diagnostics, a field test kit for the diagnosis of pathogens endemic to the Middle East, and a microfluidic assay platform with a label-free reader for performing complex biological automated assays in the field.
AB - The U.S. military has a continued interest in the development of handheld, field-usable sensors and test kits for a variety of diagnostic applications, such as traumatic brain injury (TBI) and infectious diseases. Field-use presents unique challenges for biosensor design, both for the readout unit and for the biological assay platform. We have developed robust biosensor devices that offer ultra-high sensitivity and also meet field-use needs. The systems under development include a multiplexed quantitative lateral flow test strip for TBI diagnostics, a field test kit for the diagnosis of pathogens endemic to the Middle East, and a microfluidic assay platform with a label-free reader for performing complex biological automated assays in the field.
KW - dipstick assay
KW - field-based diagnostics
KW - labelless detection
KW - lateral flow immunoassay
KW - lateral flow test strip
KW - microfluidic chips
KW - traumatic brain injury
UR - http://www.scopus.com/inward/record.url?scp=79959852958&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79959852958&partnerID=8YFLogxK
U2 - 10.1117/12.886661
DO - 10.1117/12.886661
M3 - Conference contribution
AN - SCOPUS:79959852958
SN - 9780819486035
T3 - Proceedings of SPIE - The International Society for Optical Engineering
BT - Sensing Technologies for Global Health, Military Medicine, Disaster Response, and Environmental Monitoring; and Biometric Technology for Human Identification VIII
T2 - Sensing Technologies for Global Health, Military Medicine, Disaster Response, and Environmental Monitoring; and Biometric Technology for Human Identification VIII
Y2 - 25 April 2011 through 27 April 2011
ER -