Fibre optic probes in optical spectroscopy, clinical applications

Urs Utzinger; Rebecca R. Richards-Kortum

doi:10.1016/B978-0-12-803224-4.00144-8

Fibre optic probes in optical spectroscopy, clinical applications

Urs Utzinger, Rebecca R. Richards-Kortum

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

In the clinical environment, optical techniques have been used for decades (microscope, colposcope, ophthalmoscope, endoscope, laparascope). Integration of spectroscopic devices into existing procedures is an obvious task. Fibre optic cables provide a flexible solution for adequate optical interfacing between the optical and spectroscopic device and the sample to be interrogated in situ. This article outlines fibre optic solutions for fluorescence and both elastic and inelastic scattering detection. After describing the fibre optic interface, probes for fluorescence spectroscopy followed by probes for reflectance measurements and side looking are presented. Finally, diffuser tips, refocusing and designs for Raman spectroscopy are discussed.

Original language	English (US)
Title of host publication	Encyclopedia of Spectroscopy and Spectrometry
Publisher	Elsevier
Pages	603-617
Number of pages	15
ISBN (Electronic)	9780128032244
DOIs	https://doi.org/10.1016/B978-0-12-803224-4.00144-8
State	Published - Jan 1 2016
Externally published	Yes

Keywords

Diffuser tips
Fibre optic
Fluorescent probes
Raman scattering
Reflectance probes
Refocusing
Side-looking probes

ASJC Scopus subject areas

General Chemistry

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10.1016/B978-0-12-803224-4.00144-8

Cite this

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abstract = "In the clinical environment, optical techniques have been used for decades (microscope, colposcope, ophthalmoscope, endoscope, laparascope). Integration of spectroscopic devices into existing procedures is an obvious task. Fibre optic cables provide a flexible solution for adequate optical interfacing between the optical and spectroscopic device and the sample to be interrogated in situ. This article outlines fibre optic solutions for fluorescence and both elastic and inelastic scattering detection. After describing the fibre optic interface, probes for fluorescence spectroscopy followed by probes for reflectance measurements and side looking are presented. Finally, diffuser tips, refocusing and designs for Raman spectroscopy are discussed.",

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AB - In the clinical environment, optical techniques have been used for decades (microscope, colposcope, ophthalmoscope, endoscope, laparascope). Integration of spectroscopic devices into existing procedures is an obvious task. Fibre optic cables provide a flexible solution for adequate optical interfacing between the optical and spectroscopic device and the sample to be interrogated in situ. This article outlines fibre optic solutions for fluorescence and both elastic and inelastic scattering detection. After describing the fibre optic interface, probes for fluorescence spectroscopy followed by probes for reflectance measurements and side looking are presented. Finally, diffuser tips, refocusing and designs for Raman spectroscopy are discussed.

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KW - Raman scattering

KW - Reflectance probes

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KW - Side-looking probes

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ER -

Fibre optic probes in optical spectroscopy, clinical applications

Abstract

Keywords

ASJC Scopus subject areas

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