Fibre Optic Probes in Optical Spectroscopy, Clinical Applications

Urs Utzinger, Rebecca R. Richards-Kortum

Research output: Chapter in Book/Report/Conference proceedingChapter


In the clinical environment, optical techniques have been used for decades (microscope, colposcope, ophthalmoscope, endoscope, laparascope). Integration of spectroscopic devices into existing procedures is an obvious task. Fibre optic cables provide a flexible solution for adequate optical interfacing between the optical and spectroscopic device and the sample to be interrogated in situ. This article outlines fibre optic solutions for fluorescence and both elastic and inelastic scattering detection. After describing the fibre optic interface, probes for fluorescence spectroscopy followed by probes for reflectance measurements and side looking are presented. Finally, diffuser tips, refocusing and designs for Raman spectroscopy are discussed.

Original languageEnglish (US)
Title of host publicationEncyclopedia of Spectroscopy and Spectrometry
PublisherElsevier Ltd.
Number of pages16
ISBN (Print)9780123744135
StatePublished - 1999


  • Diffuser tips
  • Fibre optic
  • Fluorescent probes
  • Raman scattering
  • Reflectance probes
  • Refocusing
  • Side-looking probes

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology


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