Fast decomposition of water and lipid using a GRASE technique with the IDEAL algorithm

Research output: Contribution to journalArticlepeer-review

24 Scopus citations


Three-point Dixon techniques achieve good lipid-water separation by estimating the phase due to field inhomogeneities. Recently it was demonstrated that the combination of an iterative algorithm (iterative decomposition of water and fat with echo asymmetry and least-squares estimation (IDEAL)) with a fast spin-echo (FSE) three-point Dixon method yielded robust lipid-water decomposition. As an alternative to FSE, the gradient-and spin-echo (GRASE) technique has been developed for efficient data collection. In this work we present a method for lipid-water separation by combining IDEAL with the GRASE technique. An approach to correct for errors in the lipid-water decomposition caused by phase distortions due to the switching of the readout gradient polarities inherent to GRASE is presented. The IDEAL-GRASE technique is demonstrated in phantoms and in vivo for various applications, including pelvic, musculoskeletal, and (breath-hold) cardiac imaging.

Original languageEnglish (US)
Pages (from-to)1047-1057
Number of pages11
JournalMagnetic Resonance in Medicine
Issue number6
StatePublished - Jun 2007


  • Chemical-shift imaging
  • Dixon
  • Lipid-water decomposition

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


Dive into the research topics of 'Fast decomposition of water and lipid using a GRASE technique with the IDEAL algorithm'. Together they form a unique fingerprint.

Cite this