Extracranial Metastases from Glioblastoma with Primitive Neuronal Components on FDG PET/CT

Matthew D. Kay; Holly E. Pariury; Arie Perry; Blair A. Winegar; Phillip H. Kuo

doi:10.1097/RLU.0000000000002896

Extracranial Metastases from Glioblastoma with Primitive Neuronal Components on FDG PET/CT

Matthew D. Kay, Holly E. Pariury, Arie Perry, Blair A. Winegar, Phillip H. Kuo

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

A 17-year-old girl with World Health Organization grade IV glioblastoma with primitive neuronal components (histone H3 G34-mutant and IDH1 wild type) underwent whole-body FDG PET/CT staging due to vertebral metastases on initial MRI. PET/CT revealed extracranial metastatic disease with spinal leptomeningeal dissemination, osseous metastases, and peritoneal seeding via a ventriculoperitoneal shunt. Glioblastoma is uncommon in pediatric patients and particularly those with primitive neuronal components. Extracranial metastases from glioblastoma are more common in those with primitive neuronal components. This case demonstrates the utility of FDG PET/CT for revealing distant metastases from glioblastoma.

Original language	English (US)
Pages (from-to)	E162-E164
Journal	Clinical nuclear medicine
Volume	45
Issue number	3
DOIs	https://doi.org/10.1097/RLU.0000000000002896
State	Published - Mar 1 2020

Keywords

PET
PET/CT
extracranial metastases
glioblastoma

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1097/RLU.0000000000002896

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title = "Extracranial Metastases from Glioblastoma with Primitive Neuronal Components on FDG PET/CT",

abstract = "A 17-year-old girl with World Health Organization grade IV glioblastoma with primitive neuronal components (histone H3 G34-mutant and IDH1 wild type) underwent whole-body FDG PET/CT staging due to vertebral metastases on initial MRI. PET/CT revealed extracranial metastatic disease with spinal leptomeningeal dissemination, osseous metastases, and peritoneal seeding via a ventriculoperitoneal shunt. Glioblastoma is uncommon in pediatric patients and particularly those with primitive neuronal components. Extracranial metastases from glioblastoma are more common in those with primitive neuronal components. This case demonstrates the utility of FDG PET/CT for revealing distant metastases from glioblastoma.",

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AU - Winegar, Blair A.

AU - Kuo, Phillip H.

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AB - A 17-year-old girl with World Health Organization grade IV glioblastoma with primitive neuronal components (histone H3 G34-mutant and IDH1 wild type) underwent whole-body FDG PET/CT staging due to vertebral metastases on initial MRI. PET/CT revealed extracranial metastatic disease with spinal leptomeningeal dissemination, osseous metastases, and peritoneal seeding via a ventriculoperitoneal shunt. Glioblastoma is uncommon in pediatric patients and particularly those with primitive neuronal components. Extracranial metastases from glioblastoma are more common in those with primitive neuronal components. This case demonstrates the utility of FDG PET/CT for revealing distant metastases from glioblastoma.

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Extracranial Metastases from Glioblastoma with Primitive Neuronal Components on FDG PET/CT

Abstract

Keywords

ASJC Scopus subject areas

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