TY - JOUR
T1 - Expert Consensus Guidelines for Stocking of Antidotes in Hospitals That Provide Emergency Care
AU - Dart, Richard C.
AU - Goldfrank, Lewis R.
AU - Erstad, Brian L.
AU - Huang, David T.
AU - Todd, Knox H.
AU - Weitz, Jeffrey
AU - Bebarta, Vikhyat S.
AU - Caravati, E. Martin
AU - Henretig, Fred M.
AU - Delbridge, Theodore R.
AU - Banner, William
AU - Schneider, Sandra M.
AU - Anderson, Victoria E.
N1 - Publisher Copyright:
© 2017 American College of Emergency Physicians
PY - 2018/3
Y1 - 2018/3
N2 - We provide recommendations for stocking of antidotes used in emergency departments (EDs). An expert panel representing diverse perspectives (clinical pharmacology, medical toxicology, critical care medicine, hematology/oncology, hospital pharmacy, emergency medicine, emergency medical services, pediatric emergency medicine, pediatric critical care medicine, poison centers, hospital administration, and public health) was formed to create recommendations for antidote stocking. Using a standardized summary of the medical literature, the primary reviewer for each antidote proposed guidelines for antidote stocking to the full panel. The panel used a formal iterative process to reach their recommendation for both the quantity of antidote that should be stocked and the acceptable timeframe for its delivery. The panel recommended consideration of 45 antidotes; 44 were recommended for stocking, of which 23 should be immediately available. In most hospitals, this timeframe requires that the antidote be stocked in a location that allows immediate availability. Another 14 antidotes were recommended for availability within 1 hour of the decision to administer, allowing the antidote to be stocked in the hospital pharmacy if the hospital has a mechanism for prompt delivery of antidotes. The panel recommended that each hospital perform a formal antidote hazard vulnerability assessment to determine its specific need for antidote stocking. Antidote administration is an important part of emergency care. These expert recommendations provide a tool for hospitals that offer emergency care to provide appropriate care of poisoned patients.
AB - We provide recommendations for stocking of antidotes used in emergency departments (EDs). An expert panel representing diverse perspectives (clinical pharmacology, medical toxicology, critical care medicine, hematology/oncology, hospital pharmacy, emergency medicine, emergency medical services, pediatric emergency medicine, pediatric critical care medicine, poison centers, hospital administration, and public health) was formed to create recommendations for antidote stocking. Using a standardized summary of the medical literature, the primary reviewer for each antidote proposed guidelines for antidote stocking to the full panel. The panel used a formal iterative process to reach their recommendation for both the quantity of antidote that should be stocked and the acceptable timeframe for its delivery. The panel recommended consideration of 45 antidotes; 44 were recommended for stocking, of which 23 should be immediately available. In most hospitals, this timeframe requires that the antidote be stocked in a location that allows immediate availability. Another 14 antidotes were recommended for availability within 1 hour of the decision to administer, allowing the antidote to be stocked in the hospital pharmacy if the hospital has a mechanism for prompt delivery of antidotes. The panel recommended that each hospital perform a formal antidote hazard vulnerability assessment to determine its specific need for antidote stocking. Antidote administration is an important part of emergency care. These expert recommendations provide a tool for hospitals that offer emergency care to provide appropriate care of poisoned patients.
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U2 - 10.1016/j.annemergmed.2017.05.021
DO - 10.1016/j.annemergmed.2017.05.021
M3 - Article
C2 - 28669553
AN - SCOPUS:84977782890
SN - 0196-0644
VL - 71
SP - 314-325.e1
JO - Annals of emergency medicine
JF - Annals of emergency medicine
IS - 3
ER -