Experimental pancreas transplantation

Erin Chang; John Renz; Rainer W.G. Gruessner

doi:10.1016/B978-0-12-814833-4.00030-7

Experimental pancreas transplantation

Erin Chang, John Renz, Rainer W.G. Gruessner

Surgery

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Animal models are an important method of scientific research. Progress in clinical transplantation was made much in part due to experimental animal models which helped to evolve the surgical techniques and methods of engraftment and eventually created a path toward human transplantation. In the field of pancreas transplantation, animal models have also provided a better understanding of transplant immunology, graft rejection, immunosuppressive therapy, and methods of organ preservation.

Original language	English (US)
Title of host publication	Transplantation, Bioengineering, and Regeneration of the Endocrine Pancreas
Subtitle of host publication	Volume 1
Publisher	Elsevier
Pages	365-373
Number of pages	9
ISBN (Electronic)	9780128148334
ISBN (Print)	9780128148341
DOIs	https://doi.org/10.1016/B978-0-12-814833-4.00030-7
State	Published - Jan 1 2019

Keywords

Large animal models
Organ preservation
Pancreas transplantation
Rejection
Small animal models
Surgical techniques
Transplant pharmacology
Xenotransplantation

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

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10.1016/B978-0-12-814833-4.00030-7

Cite this

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AB - Animal models are an important method of scientific research. Progress in clinical transplantation was made much in part due to experimental animal models which helped to evolve the surgical techniques and methods of engraftment and eventually created a path toward human transplantation. In the field of pancreas transplantation, animal models have also provided a better understanding of transplant immunology, graft rejection, immunosuppressive therapy, and methods of organ preservation.

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KW - Pancreas transplantation

KW - Rejection

KW - Small animal models

KW - Surgical techniques

KW - Transplant pharmacology

KW - Xenotransplantation

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PB - Elsevier

ER -

Experimental pancreas transplantation

Abstract

Keywords

ASJC Scopus subject areas

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