Experimental pancreas transplantation

Erin Chang, John Renz, Rainer W.G. Gruessner

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Animal models are an important method of scientific research. Progress in clinical transplantation was made much in part due to experimental animal models which helped to evolve the surgical techniques and methods of engraftment and eventually created a path toward human transplantation. In the field of pancreas transplantation, animal models have also provided a better understanding of transplant immunology, graft rejection, immunosuppressive therapy, and methods of organ preservation.

Original languageEnglish (US)
Title of host publicationTransplantation, Bioengineering, and Regeneration of the Endocrine Pancreas
Subtitle of host publicationVolume 1
PublisherElsevier
Pages365-373
Number of pages9
ISBN (Electronic)9780128148334
ISBN (Print)9780128148341
DOIs
StatePublished - Jan 1 2019
Externally publishedYes

Keywords

  • Large animal models
  • Organ preservation
  • Pancreas transplantation
  • Rejection
  • Small animal models
  • Surgical techniques
  • Transplant pharmacology
  • Xenotransplantation

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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