Evaluation of spectral discriminant functions for guidance of laser angioplasty

Kenneth M. O’Brien, Arthur F. Gmitro, Gene R. Gindi, Mark L. Stetz, Francis W. Cutruzzola, Lawrence I. Laifer, Lawrence I. Deckelbaum

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Development of a clinically acceptable laser angioplasty system has been hindered by the inability to adequately guide ablative laser radiation to atherosclerotic plaque. Low power laser-induced fluorescence spectroscopy is capable of discriminating normal and atherosclerotic arterial tissue. The purpose of this investigation was to develop and evaluate several spectral classification algorithms that would enable discrimination of atherosclerotic and normal arterial tissue by a computer controlled fluorescence guided laser angioplasty system.

Original languageEnglish (US)
Pages (from-to)116-119
Number of pages4
JournalProceedings of SPIE - The International Society for Optical Engineering
StatePublished - Jun 15 1989

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering


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