This paper examines the effectiveness of an asteroid exploration architecture comprised of multiple nanosatellite sized spacecraft deployed from a single mother ship into a heliocentric orbit in the main asteroid belt where the mothership is ideally located in region of high density. Basic mission requirements associated with a Mother-Daughter architecture are established utilizing a relatively large number (10-20) daughter spacecraft distributed from a mothership within the asteroid belt for the purpose of executing sample and return missions. A number of trade analyses are performed to establish system performance to changes in initial orbit, delta-V capability and maximum small spacecraft flight time. The balance between the initial delta-V burn and asteroid velocity matching are also examined, with a goal of minimizing the amount of fuel needed in the small spacecraft. Preliminary requirements for the system are established using these results, and a conceptual design is presented for comparison to other asteroid exploration techniques. Preliminary results indicate that the aforementioned concept of a mothership with small spacecraft is viable and should be considered as an alternative approach to first order surveying of the asteroid belt.