Evaluating ICU Clinical Severity Scoring Systems and Machine Learning Applications: APACHE IV/IVa Case Study

Baran Balkan, Patrick Essay, Vignesh Subbian

Research output: Chapter in Book/Report/Conference proceedingConference contribution

8 Scopus citations

Abstract

Clinical scoring systems have been developed for many specific applications, yet they remain underutilized for common reasons such as model inaccuracy and difficulty of use. For intensive care units specifically, the Acute Physiology and Chronic Health Evaluation (APACHE) score is used as a decision-making tool and hospital efficacy measure. In an attempt to alleviate the general underlying limitations of scoring instruments and demonstrate the utility of readily available medical databases, machine learning techniques were used to evaluate APACHE IV and IVa prediction measures in an open-source, teleICU research database. The teleICU database allowed for large-scale evaluation of APACHE IV and IVa predictions by comparing predicted values to the actual, recorded patient outcomes along with preliminary exploration of new predictive models for patient mortality and length of stay in both the hospital and the ICU. An increase in performance was observed in the newly developed models trained on the APACHE input variables highlighting avenues of future research and illustrating the utility of teleICU databases for model development and evaluation.

Original languageEnglish (US)
Title of host publication40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages4073-4076
Number of pages4
ISBN (Electronic)9781538636466
DOIs
StatePublished - Oct 26 2018
Externally publishedYes
Event40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018 - Honolulu, United States
Duration: Jul 18 2018Jul 21 2018

Publication series

NameProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
Volume2018-July
ISSN (Print)1557-170X

Conference

Conference40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018
Country/TerritoryUnited States
CityHonolulu
Period7/18/187/21/18

ASJC Scopus subject areas

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

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