Estrogen Receptors are Present in Neocortical Transplants

Erik B. Pedersen; Joan A. O’Keefe; Robert J. Handa; Anthony J. Castro

doi:10.1155/NP.1992.135

Estrogen Receptors are Present in Neocortical Transplants

Erik B. Pedersen, Joan A. O’Keefe, Robert J. Handa, Anthony J. Castro

Basic Medical Sciences, Phoenix

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Fetal neocortical tissue was grafted into neocortical lesion cavities made in newborn rats. After two weeks survival, in vitro binding of [³H]-estradiol to cytosolic preparations provided evidence of estrogen receptors within the transplants. The observed high levels correspond to previous work demonstrating elevated estrogen receptor levels during the first postnatal week in the rat cerebral cortex.

Original language	English (US)
Pages (from-to)	135-138
Number of pages	4
Journal	Journal of Neural Transplantation and Plasticity
Volume	3
Issue number	2-3
DOIs	https://doi.org/10.1155/NP.1992.135
State	Published - 1992

Keywords

cortex lesion
neural graft
newborn
rat

ASJC Scopus subject areas

Neurology
Clinical Neurology

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10.1155/NP.1992.135

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abstract = "Fetal neocortical tissue was grafted into neocortical lesion cavities made in newborn rats. After two weeks survival, in vitro binding of [3H]-estradiol to cytosolic preparations provided evidence of estrogen receptors within the transplants. The observed high levels correspond to previous work demonstrating elevated estrogen receptor levels during the first postnatal week in the rat cerebral cortex.",

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author = "Pedersen, {Erik B.} and O{\textquoteright}Keefe, {Joan A.} and Handa, {Robert J.} and Castro, {Anthony J.}",

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AU - O’Keefe, Joan A.

AU - Handa, Robert J.

AU - Castro, Anthony J.

PY - 1992

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AB - Fetal neocortical tissue was grafted into neocortical lesion cavities made in newborn rats. After two weeks survival, in vitro binding of [3H]-estradiol to cytosolic preparations provided evidence of estrogen receptors within the transplants. The observed high levels correspond to previous work demonstrating elevated estrogen receptor levels during the first postnatal week in the rat cerebral cortex.

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KW - neural graft

KW - newborn

KW - rat

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ER -

Estrogen Receptors are Present in Neocortical Transplants

Abstract

Keywords

ASJC Scopus subject areas

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