Estrogen Receptors are Present in Neocortical Transplants

Erik B. Pedersen, Joan A. O’Keefe, Robert J. Handa, Anthony J. Castro

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Fetal neocortical tissue was grafted into neocortical lesion cavities made in newborn rats. After two weeks survival, in vitro binding of [3H]-estradiol to cytosolic preparations provided evidence of estrogen receptors within the transplants. The observed high levels correspond to previous work demonstrating elevated estrogen receptor levels during the first postnatal week in the rat cerebral cortex.

Original languageEnglish (US)
Pages (from-to)135-138
Number of pages4
JournalJournal of Neural Transplantation and Plasticity
Issue number2-3
StatePublished - 1992


  • cortex lesion
  • neural graft
  • newborn
  • rat

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology


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