Estimation of response slopes in respiratory control

D. L. Sherrill, G. D. Swanson

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


The ventilatory response to changes in arterial CO2 is an index of respiratory control behavior. Methodology for estimating these response slopes must consider that there may be error in both the independent (CO2) and dependent (ventilation) variables. Recent work has suggested inherent problems in the traditional techniques of reduced major axis and has suggested more contemporary methods of directional statistics should be used. We have analyzed both techniques and developed a modified technique to overcome the problems of reduced major axis. Further, we point out several inherent problems in the use of directional statistics for respiratory data. Data from the literature serves to illustrate the concepts.

Original languageEnglish (US)
Pages (from-to)45-48
Number of pages4
JournalBiomedical Sciences Instrumentation
VolumeVol. 16
StatePublished - 1980
Externally publishedYes

ASJC Scopus subject areas

  • Biophysics
  • Medical Laboratory Technology


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