Equine Asthma: Current Understanding and Future Directions

Laurent Couetil; Jacqueline M. Cardwell; Renaud Leguillette; Melissa Mazan; Eric Richard; Dorothee Bienzle; Michela Bullone; Vinzenz Gerber; Kathleen Ivester; Jean Pierre Lavoie; James Martin; Gabriel Moran; Artur Niedźwiedź; Nicola Pusterla; Cyprianna Swiderski

doi:10.3389/fvets.2020.00450

Equine Asthma: Current Understanding and Future Directions

Laurent Couetil, Jacqueline M. Cardwell, Renaud Leguillette, Melissa Mazan, Eric Richard, Dorothee Bienzle, Michela Bullone, Vinzenz Gerber, Kathleen Ivester, Jean Pierre Lavoie, James Martin, Gabriel Moran, Artur Niedźwiedź, Nicola Pusterla, Cyprianna Swiderski

Research output: Contribution to journal › Review article › peer-review

87 Scopus citations

Abstract

The 2019 Havemeyer Workshop brought together researchers and clinicians to discuss the latest information on Equine Asthma and provide future research directions. Current clinical and molecular asthma phenotypes and endotypes in humans were discussed and compared to asthma phenotypes in horses. The role of infectious and non-infectious causes of equine asthma, genetic factors and proposed disease pathophysiology were reviewed. Diagnostic limitations were evident by the limited number of tests and biomarkers available to field practitioners. The participants emphasized the need for more accessible, standardized diagnostics that would help identify specific phenotypes and endotypes in order to create more targeted treatments or management strategies. One important outcome of the workshop was the creation of the Equine Asthma Group that will facilitate communication between veterinary practice and research communities through published and easily accessible guidelines and foster research collaboration.

Original language	English (US)
Article number	450
Journal	Frontiers in Veterinary Science
Volume	7
DOIs	https://doi.org/10.3389/fvets.2020.00450
State	Published - Jul 30 2020
Externally published	Yes

Keywords

biomarkers
endotype
heaves
inflammatory airway disease
phenotype
recurrent airway obstruction

ASJC Scopus subject areas

General Veterinary

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10.3389/fvets.2020.00450

Cite this

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title = "Equine Asthma: Current Understanding and Future Directions",

abstract = "The 2019 Havemeyer Workshop brought together researchers and clinicians to discuss the latest information on Equine Asthma and provide future research directions. Current clinical and molecular asthma phenotypes and endotypes in humans were discussed and compared to asthma phenotypes in horses. The role of infectious and non-infectious causes of equine asthma, genetic factors and proposed disease pathophysiology were reviewed. Diagnostic limitations were evident by the limited number of tests and biomarkers available to field practitioners. The participants emphasized the need for more accessible, standardized diagnostics that would help identify specific phenotypes and endotypes in order to create more targeted treatments or management strategies. One important outcome of the workshop was the creation of the Equine Asthma Group that will facilitate communication between veterinary practice and research communities through published and easily accessible guidelines and foster research collaboration.",

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author = "Laurent Couetil and Cardwell, {Jacqueline M.} and Renaud Leguillette and Melissa Mazan and Eric Richard and Dorothee Bienzle and Michela Bullone and Vinzenz Gerber and Kathleen Ivester and Lavoie, {Jean Pierre} and James Martin and Gabriel Moran and Artur Nied{\'z}wied{\'z} and Nicola Pusterla and Cyprianna Swiderski",

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doi = "10.3389/fvets.2020.00450",

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AU - Mazan, Melissa

AU - Richard, Eric

AU - Bienzle, Dorothee

AU - Bullone, Michela

AU - Gerber, Vinzenz

AU - Ivester, Kathleen

AU - Lavoie, Jean Pierre

AU - Martin, James

AU - Moran, Gabriel

AU - Niedźwiedź, Artur

AU - Pusterla, Nicola

AU - Swiderski, Cyprianna

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AB - The 2019 Havemeyer Workshop brought together researchers and clinicians to discuss the latest information on Equine Asthma and provide future research directions. Current clinical and molecular asthma phenotypes and endotypes in humans were discussed and compared to asthma phenotypes in horses. The role of infectious and non-infectious causes of equine asthma, genetic factors and proposed disease pathophysiology were reviewed. Diagnostic limitations were evident by the limited number of tests and biomarkers available to field practitioners. The participants emphasized the need for more accessible, standardized diagnostics that would help identify specific phenotypes and endotypes in order to create more targeted treatments or management strategies. One important outcome of the workshop was the creation of the Equine Asthma Group that will facilitate communication between veterinary practice and research communities through published and easily accessible guidelines and foster research collaboration.

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KW - heaves

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Equine Asthma: Current Understanding and Future Directions

Abstract

Keywords

ASJC Scopus subject areas

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