EpiphaNet: An interactive tool to support biomedical discoveries

Trevor Cohen, G. Kerr Whitfield, Roger W. Schvaneveldt, Kavitha Mukund, Thomas Rindflesch

Research output: Contribution to journalArticlepeer-review

42 Scopus citations


Background: EpiphaNet (http://epiphanet.uth.tmc.edu) is an interactive knowledge discovery system, which enables researchers to explore visually sets of relations extracted from MEDLINE using a combination of language processing techniques. In this paper, we discuss the theoretical and methodological foundations of the system, and evaluate the utility of the models that underlie it for literature-based discovery. In addition, we present a summary of results drawn from a qualitative analysis of over six hours of interaction with the system by basic medical scientists. Results: The system is able to simulate open and closed discovery, and is shown to generate associations that are both surprising and interesting within the area of expertise of the researchers concerned. Conclusions: EpiphaNet provides an interactive visual representation of associations between concepts, which is derived from distributional statistics drawn from across the spectrum of biomedical citations in MEDLINE. This tool is available online, providing biomedical scientists with the opportunity to identify and explore associations of interest to them.

Original languageEnglish (US)
Pages (from-to)21-49
Number of pages29
JournalJournal of Biomedical Discovery and Collaboration
Issue number1
StatePublished - 2010
Externally publishedYes

ASJC Scopus subject areas

  • Health Informatics
  • Computer Science Applications
  • History and Philosophy of Science


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